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TCC1_MOUSE
ID   TCC1_MOUSE              Reviewed;         167 AA.
AC   P01853;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-1986, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=T-cell receptor gamma chain C region C10.5;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=3917858; DOI=10.1016/0092-8674(85)90140-0;
RA   Hayday A.C., Saito H., Gillies S.D., Kranz D.M., Tanigawa G., Eisen H.N.,
RA   Tonegawa S.;
RT   "Structure, organization, and somatic rearrangement of T cell gamma
RT   genes.";
RL   Cell 40:259-269(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE (CLONE PHDS4/PHDS203).
RC   STRAIN=BALB.B;
RX   PubMed=6330561; DOI=10.1038/309757a0;
RA   Saito H., Kranz D.M., Takagaki Y., Hayday A.C., Eisen H.N., Tonegawa S.;
RT   "Complete primary structure of a heterodimeric T-cell receptor deduced from
RT   cDNA sequences.";
RL   Nature 309:757-762(1984).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=3785427; DOI=10.1038/324482a0;
RA   Yoshikai Y., Reis M.D., Mak T.W.;
RT   "Athymic mice express a high level of functional gamma-chain but greatly
RT   reduced levels of alpha- and beta-chain T-cell receptor messages.";
RL   Nature 324:482-485(1986).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: This mRNA was isolated from a cytotoxic T-lymphocyte.
CC       The gene corresponding to this mRNA is rearranged specifically in T-
CC       cells and its organization is similar to an Ig gene, with V (or V+D),
CC       J, and C regions.
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DR   PIR; B90859; RWMSC1.
DR   AlphaFoldDB; P01853; -.
DR   SMR; P01853; -.
DR   PRIDE; P01853; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01853; protein.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Immunoglobulin domain; Membrane; Receptor; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           <1..167
FT                   /note="T-cell receptor gamma chain C region C10.5"
FT                   /id="PRO_0000184531"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        156..167
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..134
FT                   /note="C region"
FT   NON_TER         1
SQ   SEQUENCE   167 AA;  19101 MW;  07AB517983A4B864 CRC64;
     DKRLDADISP KPTIFLPSVA ETNLHKTGTY LCLLEKFFPD VIRVYWKEKN GNTILDSQEG
     DTLKTKGTYM KFSWLTVPER AMGKEHSCIV KHENNKGGAD QEIFFPSIKK VATTCWQDKN
     DVLQFQFTST SAYYTYLLLL LKSVIYLAII SFSLLRRTSV CGNEKKS
 
 
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