ID   TCC_TERAN               Reviewed;          98 AA.
AC   P0DN45;
DT   09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT   09-DEC-2015, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=Tan_12Cys {ECO:0000303|PubMed:26025559};
DE   Flags: Precursor;
OS   Terebra anilis (Auger snail) (Cinguloterebra anilis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Terebridae; Terebra.
OX   NCBI_TaxID=553697;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=26025559; DOI=10.1093/gbe/evv104;
RA   Gorson J., Ramrattan G., Verdes A., Wright E.M., Kantor Y.,
RA   Rajaram Srinivasan R., Musunuri R., Packer D., Albano G., Qiu W.G.,
RA   Holford M.;
RT   "Molecular diversity and gene evolution of the venom arsenal of Terebridae
RT   predatory marine snails.";
RL   Genome Biol. Evol. 7:1761-1778(2015).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:26025559}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:26025559}.
CC   -!- DOMAIN: The cysteine framework is C-CC-CC-C-C-C-C-C-C-C.
CC   -!- PTM: Contains 6 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the teretoxin C (TC) superfamily.
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DR   AlphaFoldDB; P0DN45; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cleavage on pair of basic residues; Disulfide bond; Secreted; Signal;
KW   Toxin.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   PROPEP          22..28
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000435054"
FT   CHAIN           29..98
FT                   /note="Tan_12Cys"
FT                   /id="PRO_0000435055"
SQ   SEQUENCE   98 AA;  11259 MW;  867FB90BC705276D CRC64;
     MNLKVLFLLA MVLVTLCLGE DRVTDRRKFC KCCASCCVSG RNIDGDCPPH GNQQFCHFCN
     REKVKIKRDC RSNQTAYQHC MEYHIQCASV KNHVCTDQ