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TCF19_MACMU
ID   TCF19_MACMU             Reviewed;         345 AA.
AC   Q5TM48;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Transcription factor 19;
DE            Short=TCF-19;
GN   Name=TCF19;
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15269276; DOI=10.1093/molbev/msh216;
RA   Kulski J.K., Anzai T., Shiina T., Inoko H.;
RT   "Rhesus macaque class I duplicon structures, organization, and evolution
RT   within the alpha block of the major histocompatibility complex.";
RL   Mol. Biol. Evol. 21:2079-2091(2004).
CC   -!- FUNCTION: Potential trans-activating factor that could play an
CC       important role in the transcription of genes required for the later
CC       stages of cell cycle progression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; AB128049; BAD69746.1; -; Genomic_DNA.
DR   RefSeq; NP_001108423.1; NM_001114951.1.
DR   RefSeq; XP_014991391.1; XM_015135905.1.
DR   AlphaFoldDB; Q5TM48; -.
DR   SMR; Q5TM48; -.
DR   STRING; 9544.ENSMMUP00000020588; -.
DR   PRIDE; Q5TM48; -.
DR   GeneID; 714141; -.
DR   KEGG; mcc:714141; -.
DR   CTD; 6941; -.
DR   eggNOG; ENOG502RHCY; Eukaryota.
DR   HOGENOM; CLU_041089_0_0_1; -.
DR   InParanoid; Q5TM48; -.
DR   OrthoDB; 1106192at2759; -.
DR   Proteomes; UP000006718; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   CDD; cd00060; FHA; 1.
DR   CDD; cd15609; PHD_TCF19; 1.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR042803; TCF19.
DR   InterPro; IPR039095; TCF19_PHD.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR15464; PTHR15464; 2.
DR   Pfam; PF00498; FHA; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   SUPFAM; SSF57903; SSF57903; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..345
FT                   /note="Transcription factor 19"
FT                   /id="PRO_0000232912"
FT   DOMAIN          31..88
FT                   /note="FHA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00086"
FT   ZN_FING         293..342
FT                   /note="PHD-type"
FT   REGION          138..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          190..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..215
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   345 AA;  37073 MW;  B01C902B4F6FBE11 CRC64;
     MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP GLISGIHAEL
     HAEPRGDDWR VSLEDHSLQG TLVNNVRLPR GHRLELSDGD LLTFGPEGPP GTSPSEFYFM
     FQQVRVKPQD FAAITIPRSR GETRAGAGFR PMLPSQGAPQ RPLSTLSPAP KATLILNSIG
     SLSKLRPQPL TFSPSWGGPR SLPVPAPPGE VGNAPSAPPP RNRRKSVHRV LAELDDDSQP
     SESPPPVLME PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE PCAAPCCCLP
     QEETVAWVQC DGCDVWFHVA CVGCSIQAAR EADFRCPGCR AGIQT
 
 
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