ID   TCMJ_STRGA              Reviewed;         149 AA.
AC   P16558;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 2.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Tetracenomycin polyketide synthesis protein TcmJ;
GN   Name=tcmJ;
OS   Streptomyces glaucescens.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 40716 / ETH 22794 / Tue 49;
RA   Guilfoile P.G., Hutchinson C.R.;
RL   Submitted (FEB-1992) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 120-149.
RC   STRAIN=DSM 40716 / ETH 22794 / Tue 49;
RX   PubMed=2684656; DOI=10.1002/j.1460-2075.1989.tb08414.x;
RA   Bibb M.J., Biro S., Motamedi H., Collins J.F., Hutchinson C.R.;
RT   "Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI
RT   genes provides key information about the enzymology of polyketide
RT   antibiotic biosynthesis.";
RL   EMBO J. 8:2727-2736(1989).
CC   -!- FUNCTION: Possibly required for conversion of tetracenomycin F2 to
CC       tetracenomycin D3.
CC   -!- PATHWAY: Antibiotic biosynthesis; tetracenomycin C biosynthesis.
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DR   EMBL; M80674; AAA67514.1; -; Genomic_DNA.
DR   EMBL; X15312; CAA33368.1; -; Genomic_DNA.
DR   PIR; C53291; C53291.
DR   PIR; S27692; S27692.
DR   AlphaFoldDB; P16558; -.
DR   SMR; P16558; -.
DR   STRING; 1907.SGLAU_26350; -.
DR   eggNOG; COG0662; Bacteria.
DR   BioCyc; MetaCyc:MON-18609; -.
DR   UniPathway; UPA00174; -.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR013096; Cupin_2.
DR   InterPro; IPR016672; Polyketide_Synth_CurC_prd.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   Pfam; PF07883; Cupin_2; 1.
DR   PIRSF; PIRSF016602; CurC_prd; 1.
DR   SUPFAM; SSF51182; SSF51182; 1.
PE   4: Predicted;
KW   Antibiotic biosynthesis.
FT   CHAIN           1..149
FT                   /note="Tetracenomycin polyketide synthesis protein TcmJ"
FT                   /id="PRO_0000072455"
FT   REGION          127..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   149 AA;  15906 MW;  AA521BF126F5A84A CRC64;
     MTTAQHEGEQ TVAAAAKIAM SSVAPSHRQG GSTRALLTPS SVGATSGFLG HIELAPGESV
     TEHYHPFSDK YLYLIEGSLV VRVNGEEVRL ERDEALFVTR GQRHRIENRG NVPARVVFQI
     SPLAPRPELG HVDTEPVPNP AAAPPKVGG