ID   TCP12_ARATH             Reviewed;         356 AA.
AC   A0AQW4; Q9CA43;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Transcription factor TCP12;
DE   AltName: Full=Protein BRANCHED 2;
GN   Name=TCP12; Synonyms=BRC2; OrderedLocusNames=At1g68800; ORFNames=F14K14.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL
RP   STAGE, SUBCELLULAR LOCATION, INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17307924; DOI=10.1105/tpc.106.048934;
RA   Aguilar-Martinez J.A., Poza-Carrion C., Cubas P.;
RT   "Arabidopsis BRANCHED1 acts as an integrator of branching signals within
RT   axillary buds.";
RL   Plant Cell 19:458-472(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Transcription factor that prevents axillary bud outgrowth.
CC       May also delay early axillary bud development. Probably involved in the
CC       auxin-induced control of apical dominance.
CC       {ECO:0000269|PubMed:17307924}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00701,
CC       ECO:0000269|PubMed:17307924}.
CC   -!- TISSUE SPECIFICITY: Expressed in axillary buds, and, to a lower extent,
CC       in axillary structures such as flowers and siliques.
CC       {ECO:0000269|PubMed:17307924}.
CC   -!- DEVELOPMENTAL STAGE: Detected in axillary mersitems which appears in
CC       the axils of leaves after flowering. During bud vegetative development,
CC       down-regulated in the outer layers of the meristem, but accumulates
CC       transiently in young leaf primordia. In buds bearing flowers,
CC       restricted to the provascular tissue underlying the bud. Accumulates in
CC       axillary buds, but disappears at the time of bud outgrowth.
CC       {ECO:0000269|PubMed:17307924}.
CC   -!- INDUCTION: Repressed transiently after shoot apical meristem (SAM)
CC       decapitation (release from apical dominance).
CC       {ECO:0000269|PubMed:17307924}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG52043.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AM408561; CAL64011.1; -; mRNA.
DR   EMBL; AC011914; AAG52043.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE34841.1; -; Genomic_DNA.
DR   PIR; G96712; G96712.
DR   RefSeq; NP_177047.2; NM_105554.3.
DR   AlphaFoldDB; A0AQW4; -.
DR   SMR; A0AQW4; -.
DR   BioGRID; 28433; 1.
DR   STRING; 3702.AT1G68800.1; -.
DR   PaxDb; A0AQW4; -.
DR   PRIDE; A0AQW4; -.
DR   EnsemblPlants; AT1G68800.1; AT1G68800.1; AT1G68800.
DR   GeneID; 843212; -.
DR   Gramene; AT1G68800.1; AT1G68800.1; AT1G68800.
DR   KEGG; ath:AT1G68800; -.
DR   Araport; AT1G68800; -.
DR   TAIR; locus:2012403; AT1G68800.
DR   eggNOG; ENOG502QUQ6; Eukaryota.
DR   HOGENOM; CLU_861523_0_0_1; -.
DR   InParanoid; A0AQW4; -.
DR   PhylomeDB; A0AQW4; -.
DR   PRO; PR:A0AQW4; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; A0AQW4; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:2000032; P:regulation of secondary shoot formation; IMP:TAIR.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   InterPro; IPR017888; CYC/TB1_R_domain.
DR   InterPro; IPR017887; TF_TCP_subgr.
DR   InterPro; IPR005333; Transcription_factor_TCP.
DR   PANTHER; PTHR31072; PTHR31072; 1.
DR   Pfam; PF03634; TCP; 1.
DR   PROSITE; PS51370; R; 1.
DR   PROSITE; PS51369; TCP; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..356
FT                   /note="Transcription factor TCP12"
FT                   /id="PRO_0000330786"
FT   DOMAIN          112..170
FT                   /note="TCP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT   DOMAIN          216..233
FT                   /note="R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00702"
FT   REGION          173..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   356 AA;  41366 MW;  DD3AABE85C6D2C71 CRC64;
     MFPSLDTNGY DLFDPFIPHQ TTMFPSFITH IQSPNSHHHY SSPSFPFSSD FLESFDESFL
     INQFLLQQQD VAANVVESPW KFCKKLELKK KNEKCVDGST SQEVQWRRTV KKRDRHSKIC
     TAQGPRDRRM RLSLQIARKF FDLQDMLGFD KASKTIEWLF SKSKTSIKQL KERVAASEGG
     GKDEHLQVDE KEKDETLKLR VSKRRTKTME SSFKTKESRE RARKRARERT MAKMKMRLFE
     TSETISDPHQ ETREIKITNG VQLLEKENKE QEWSNTNDVH MVEYQMDSVS IIEKFLGLTS
     DSSSSSIFGD SEECYTSLSS VRGMSTPREH NTTSIATVDE EKSPISSFSL YDYLCY