TCP1_ARATH
ID TCP1_ARATH Reviewed; 359 AA.
AC Q9FYG7;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Transcription factor TCP1;
GN Name=TCP1; OrderedLocusNames=At1g67260; ORFNames=F1N21.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX DOI=10.1002/cfg.146;
RA Paz-Ares J., Valencia A., Costantino P., Vittorioso P., Davies B.,
RA Gilmartin P., Giraudat J., Parcy F., Reindl A., Sablowski R., Coupland G.,
RA Martin C., Angenent G.C., Baeumlein H., Mock H.-P., Carbonero P.,
RA Colombo L., Tonelli C., Engstroem P., Droege-Laser W., Gatz C.,
RA Kavanagh T., Kushnir S., Zabeau M., Laux T., Hordsworth M., Ruberti I.,
RA Ratcliff F., Smeekens S., Somssich I., Weisshaar B., Traas J.;
RT "REGIA, an EU project on functional genomics of transcription factors from
RT Arabidopsis thaliana.";
RL Comp. Funct. Genomics 3:102-108(2002).
RN [4]
RP TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=11470410; DOI=10.1016/s0960-9822(01)00295-0;
RA Cubas P., Coen E., Zapater J.M.;
RT "Ancient asymmetries in the evolution of flowers.";
RL Curr. Biol. 11:1050-1052(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17307924; DOI=10.1105/tpc.106.048934;
RA Aguilar-Martinez J.A., Poza-Carrion C., Cubas P.;
RT "Arabidopsis BRANCHED1 acts as an integrator of branching signals within
RT axillary buds.";
RL Plant Cell 19:458-472(2007).
RN [6]
RP FUNCTION.
RX PubMed=17940055; DOI=10.1073/pnas.0705338104;
RA Busch A., Zachgo S.;
RT "Control of corolla monosymmetry in the Brassicaceae Iberis amara.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:16714-16719(2007).
RN [7]
RP INTERACTION WITH SPL.
RX PubMed=25527103; DOI=10.1016/j.jgg.2014.08.009;
RA Chen G.H., Sun J.Y., Liu M., Liu J., Yang W.C.;
RT "SPOROCYTELESS is a novel embryophyte-specific transcription repressor that
RT interacts with TPL and TCP proteins in Arabidopsis.";
RL J. Genet. Genomics 41:617-625(2014).
CC -!- FUNCTION: Involved in petal morphogenesis.
CC {ECO:0000269|PubMed:17940055}.
CC -!- SUBUNIT: Interacts with SPL. {ECO:0000269|PubMed:25527103}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9FYG7-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Axillary shoot and floral meristems.
CC {ECO:0000269|PubMed:11470410}.
CC -!- DEVELOPMENTAL STAGE: Expressed transiently in early stages of floral
CC meristems development but continuously in axillary shoot meristems,
CC specifically in the dorsal part (adaxial).
CC {ECO:0000269|PubMed:11470410}.
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DR EMBL; AC002130; AAG00255.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34617.1; -; Genomic_DNA.
DR EMBL; DR751457; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; DR751458; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; D96696; D96696.
DR RefSeq; NP_001077781.1; NM_001084312.1. [Q9FYG7-1]
DR AlphaFoldDB; Q9FYG7; -.
DR SMR; Q9FYG7; -.
DR BioGRID; 528019; 27.
DR IntAct; Q9FYG7; 23.
DR STRING; 3702.AT1G67260.1; -.
DR PaxDb; Q9FYG7; -.
DR PRIDE; Q9FYG7; -.
DR EnsemblPlants; AT1G67260.1; AT1G67260.1; AT1G67260. [Q9FYG7-1]
DR GeneID; 3767658; -.
DR Gramene; AT1G67260.1; AT1G67260.1; AT1G67260. [Q9FYG7-1]
DR KEGG; ath:AT1G67260; -.
DR Araport; AT1G67260; -.
DR TAIR; locus:2019594; AT1G67260.
DR eggNOG; ENOG502QUQ6; Eukaryota.
DR InParanoid; Q9FYG7; -.
DR OrthoDB; 1154879at2759; -.
DR PRO; PR:Q9FYG7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FYG7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; ISS:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009908; P:flower development; TAS:TAIR.
DR GO; GO:2000032; P:regulation of secondary shoot formation; IBA:GO_Central.
DR InterPro; IPR017888; CYC/TB1_R_domain.
DR InterPro; IPR017887; TF_TCP_subgr.
DR InterPro; IPR005333; Transcription_factor_TCP.
DR PANTHER; PTHR31072; PTHR31072; 1.
DR Pfam; PF03634; TCP; 1.
DR PROSITE; PS51370; R; 1.
DR PROSITE; PS51369; TCP; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Developmental protein; DNA-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..359
FT /note="Transcription factor TCP1"
FT /id="PRO_0000330775"
FT DOMAIN 87..145
FT /note="TCP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT DOMAIN 216..233
FT /note="R"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00702"
FT REGION 157..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 255
FT /note="K -> Q (in Ref. 3; DR751457/DR751458)"
FT /evidence="ECO:0000305"
FT CONFLICT 261
FT /note="N -> H (in Ref. 3; DR751457/DR751458)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 359 AA; 40754 MW; A0CAA192D56A1E0B CRC64;
MSSSTNDYND GNNNGVYPLS LYLSSLSGHQ DIIHNPYNHQ LKASPGHMVS AVPESLIDYM
AFKSNNVVNQ QGFEFPEVSK EIKKVVKKDR HSKIQTAQGI RDRRVRLSIG IARQFFDLQD
MLGFDKASKT LDWLLKKSRK AIKEVVQAKN LNNDDEDFGN IGGDVEQEEE KEEDDNGDKS
FVYGLSPGYG EEEVVCEATK AGIRKKKSEL RNISSKGLGA KARGKAKERT KEMMAYDNPE
TASDITQSEI MDPFKRSIVF NEGEDMTHLF YKEPIEEFDN QESILTNMTL PTKMGQSYNQ
NNGILMLVDQ SSSSNYNTFL PQNLDYSYDQ NPFHDQTLYV VTDKNFPKGK VWIQDSFVN
