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TCP24_ARATH
ID   TCP24_ARATH             Reviewed;         324 AA.
AC   Q9C758;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Transcription factor TCP24;
GN   Name=TCP24; OrderedLocusNames=At1g30210; ORFNames=F12P21.11;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17307924; DOI=10.1105/tpc.106.048934;
RA   Aguilar-Martinez J.A., Poza-Carrion C., Cubas P.;
RT   "Arabidopsis BRANCHED1 acts as an integrator of branching signals within
RT   axillary buds.";
RL   Plant Cell 19:458-472(2007).
RN   [5]
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=17307931; DOI=10.1105/tpc.106.044792;
RA   Koyama T., Furutani M., Tasaka M., Ohme-Takagi M.;
RT   "TCP transcription factors control the morphology of shoot lateral organs
RT   via negative regulation of the expression of boundary-specific genes in
RT   Arabidopsis.";
RL   Plant Cell 19:473-484(2007).
RN   [6]
RP   FUNCTION, AND IDENTIFICATION IN ABAP1-TCP24 COMPLEX.
RX   PubMed=18818695; DOI=10.1038/emboj.2008.191;
RA   Masuda H.P., Cabral L.M., De Veylder L., Tanurdzic M.,
RA   de Almeida Engler J., Geelen D., Inze D., Martienssen R.A., Ferreira P.C.,
RA   Hemerly A.S.;
RT   "ABAP1 is a novel plant Armadillo BTB protein involved in DNA replication
RT   and transcription.";
RL   EMBO J. 27:2746-2756(2008).
RN   [7]
RP   INTERACTION WITH SPL.
RX   PubMed=25527103; DOI=10.1016/j.jgg.2014.08.009;
RA   Chen G.H., Sun J.Y., Liu M., Liu J., Yang W.C.;
RT   "SPOROCYTELESS is a novel embryophyte-specific transcription repressor that
RT   interacts with TPL and TCP proteins in Arabidopsis.";
RL   J. Genet. Genomics 41:617-625(2014).
RN   [8]
RP   FUNCTION, INTERACTION WITH SPL, AND DEVELOPMENTAL STAGE.
RX   PubMed=25378179; DOI=10.1038/cr.2014.145;
RA   Wei B., Zhang J., Pang C., Yu H., Guo D., Jiang H., Ding M., Chen Z.,
RA   Tao Q., Gu H., Qu L.J., Qin G.;
RT   "The molecular mechanism of sporocyteless/nozzle in controlling Arabidopsis
RT   ovule development.";
RL   Cell Res. 25:121-134(2015).
CC   -!- FUNCTION: Plays a pivotal role in the control of morphogenesis of shoot
CC       organs by negatively regulating the expression of boundary-specific
CC       genes such as CUC genes, probably through the induction of miRNA (e.g.
CC       miR164). In association with ABAP1, exerts a negative role in cell
CC       proliferation in leaves, possibly by inhibiting mitotic DNA
CC       replication. Participates in ovule develpment (PubMed:25378179).
CC       {ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:18818695,
CC       ECO:0000269|PubMed:25378179}.
CC   -!- SUBUNIT: Forms a heterodimeric complex with ABAP1 (PubMed:18818695).
CC       Interacts with SPL (PubMed:25527103, PubMed:25378179).
CC       {ECO:0000269|PubMed:18818695, ECO:0000269|PubMed:25378179,
CC       ECO:0000269|PubMed:25527103}.
CC   -!- INTERACTION:
CC       Q9C758; B7U179: ABAP1; NbExp=4; IntAct=EBI-8079833, EBI-541722;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in cotyledons, particularly in the
CC       vascular region, in leaves, roots, stems, buds, flowers and siliques.
CC       {ECO:0000269|PubMed:17307931}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during ovule development
CC       (PubMed:25378179). {ECO:0000269|PubMed:25378179}.
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DR   EMBL; AC073506; AAG50562.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE31192.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE31193.1; -; Genomic_DNA.
DR   EMBL; AY035008; AAK59513.1; -; mRNA.
DR   EMBL; AY057672; AAL15303.1; -; mRNA.
DR   EMBL; AY113898; AAM44946.1; -; mRNA.
DR   PIR; C86426; C86426.
DR   RefSeq; NP_564351.1; NM_102760.3.
DR   RefSeq; NP_849730.1; NM_179399.3.
DR   AlphaFoldDB; Q9C758; -.
DR   SMR; Q9C758; -.
DR   BioGRID; 25136; 18.
DR   IntAct; Q9C758; 2.
DR   MINT; Q9C758; -.
DR   STRING; 3702.AT1G30210.1; -.
DR   PaxDb; Q9C758; -.
DR   PRIDE; Q9C758; -.
DR   ProteomicsDB; 234149; -.
DR   EnsemblPlants; AT1G30210.1; AT1G30210.1; AT1G30210.
DR   EnsemblPlants; AT1G30210.2; AT1G30210.2; AT1G30210.
DR   GeneID; 839901; -.
DR   Gramene; AT1G30210.1; AT1G30210.1; AT1G30210.
DR   Gramene; AT1G30210.2; AT1G30210.2; AT1G30210.
DR   KEGG; ath:AT1G30210; -.
DR   Araport; AT1G30210; -.
DR   TAIR; locus:2009797; AT1G30210.
DR   eggNOG; ENOG502QQFU; Eukaryota.
DR   HOGENOM; CLU_036572_0_0_1; -.
DR   InParanoid; Q9C758; -.
DR   OMA; QETDIAH; -.
DR   OrthoDB; 1110972at2759; -.
DR   PhylomeDB; Q9C758; -.
DR   PRO; PR:Q9C758; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9C758; baseline and differential.
DR   Genevisible; Q9C758; AT.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IPI:TAIR.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0048366; P:leaf development; IMP:TAIR.
DR   GO; GO:0008285; P:negative regulation of cell population proliferation; IGI:UniProtKB.
DR   GO; GO:2000032; P:regulation of secondary shoot formation; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   InterPro; IPR017888; CYC/TB1_R_domain.
DR   InterPro; IPR017887; TF_TCP_subgr.
DR   InterPro; IPR005333; Transcription_factor_TCP.
DR   PANTHER; PTHR31072; PTHR31072; 1.
DR   Pfam; PF03634; TCP; 1.
DR   PROSITE; PS51370; R; 1.
DR   PROSITE; PS51369; TCP; 1.
PE   1: Evidence at protein level;
KW   Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..324
FT                   /note="Transcription factor TCP24"
FT                   /id="PRO_0000330798"
FT   DOMAIN          50..108
FT                   /note="TCP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT   DOMAIN          144..162
FT                   /note="R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00702"
FT   REGION          122..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          261..297
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..215
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..284
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   324 AA;  36377 MW;  0AE0E392AC993A82 CRC64;
     MEVDEDIELQ KHQEQQSRKL QRFSEDNTGL MRNWNNPSSR IIRVSRASGG KDRHSKVLTS
     KGLRDRRIRL SVATAIQFYD LQDRLGFDQP SKAVEWLINA ASDSITDLPL LNTNFDHLDQ
     NQNQTKSACS SGTSESSLLS LSRTEIRGKA RERARERTAK DRDKDLQNAH SSFTQLLTGG
     FDQQPSNRNW TGGSDCFNPV QLQIPNSSSQ EPMNHPFSFV PDYNFGISSS SSAINGGYSS
     RGTLQSNSQS LFLNNNNNIT QRSSISSSSS SSSPMDSQSI SFFMATPPPL DHHNHQLPET
     FDGRLYLYYG EGNRSSDDKA KERR
 
 
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