TCP5_ARATH
ID TCP5_ARATH Reviewed; 360 AA.
AC Q9FME3;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Transcription factor TCP5;
GN Name=TCP5; OrderedLocusNames=At5g60970; ORFNames=MSL3.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17307924; DOI=10.1105/tpc.106.048934;
RA Aguilar-Martinez J.A., Poza-Carrion C., Cubas P.;
RT "Arabidopsis BRANCHED1 acts as an integrator of branching signals within
RT axillary buds.";
RL Plant Cell 19:458-472(2007).
RN [5]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=17307931; DOI=10.1105/tpc.106.044792;
RA Koyama T., Furutani M., Tasaka M., Ohme-Takagi M.;
RT "TCP transcription factors control the morphology of shoot lateral organs
RT via negative regulation of the expression of boundary-specific genes in
RT Arabidopsis.";
RL Plant Cell 19:473-484(2007).
RN [6]
RP INTERACTION WITH SPL.
RX PubMed=25527103; DOI=10.1016/j.jgg.2014.08.009;
RA Chen G.H., Sun J.Y., Liu M., Liu J., Yang W.C.;
RT "SPOROCYTELESS is a novel embryophyte-specific transcription repressor that
RT interacts with TPL and TCP proteins in Arabidopsis.";
RL J. Genet. Genomics 41:617-625(2014).
RN [7]
RP FUNCTION, INTERACTION WITH SPL, AND DEVELOPMENTAL STAGE.
RX PubMed=25378179; DOI=10.1038/cr.2014.145;
RA Wei B., Zhang J., Pang C., Yu H., Guo D., Jiang H., Ding M., Chen Z.,
RA Tao Q., Gu H., Qu L.J., Qin G.;
RT "The molecular mechanism of sporocyteless/nozzle in controlling Arabidopsis
RT ovule development.";
RL Cell Res. 25:121-134(2015).
CC -!- FUNCTION: Plays a pivotal role in the control of morphogenesis of shoot
CC organs by negatively regulating the expression of boundary-specific
CC genes such as CUC genes, probably through the induction of miRNA (e.g.
CC miR164). Participates in ovule develpment (PubMed:25378179).
CC {ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:25378179}.
CC -!- SUBUNIT: Interacts with SPL. {ECO:0000269|PubMed:25378179,
CC ECO:0000269|PubMed:25527103}.
CC -!- INTERACTION:
CC Q9FME3; C0SUZ3: At1g35490; NbExp=3; IntAct=EBI-15192251, EBI-15192249;
CC Q9FME3; F4K1A8: At5g26749; NbExp=3; IntAct=EBI-15192251, EBI-15191587;
CC Q9FME3; O04292: ATHB-9; NbExp=4; IntAct=EBI-15192251, EBI-1536772;
CC Q9FME3; F4IF36: FGT1; NbExp=4; IntAct=EBI-15192251, EBI-15205608;
CC Q9FME3; Q9LXD8: HEC3; NbExp=3; IntAct=EBI-15192251, EBI-1536734;
CC Q9FME3; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-15192251, EBI-2466050;
CC Q9FME3; Q9C9L2: TCP15; NbExp=4; IntAct=EBI-15192251, EBI-4426144;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in cotyledons, particularly in the
CC vascular region, in leaves, buds, flowers and immature siliques.
CC {ECO:0000269|PubMed:17307931}.
CC -!- DEVELOPMENTAL STAGE: Expressed during ovule development
CC (PubMed:25378179). {ECO:0000269|PubMed:25378179}.
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DR EMBL; AB008269; BAB10646.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97405.1; -; Genomic_DNA.
DR EMBL; BT029489; ABL66746.1; -; mRNA.
DR RefSeq; NP_200905.1; NM_125490.3.
DR AlphaFoldDB; Q9FME3; -.
DR SMR; Q9FME3; -.
DR BioGRID; 21462; 81.
DR IntAct; Q9FME3; 68.
DR STRING; 3702.AT5G60970.1; -.
DR PaxDb; Q9FME3; -.
DR PRIDE; Q9FME3; -.
DR ProteomicsDB; 232995; -.
DR EnsemblPlants; AT5G60970.1; AT5G60970.1; AT5G60970.
DR GeneID; 836218; -.
DR Gramene; AT5G60970.1; AT5G60970.1; AT5G60970.
DR KEGG; ath:AT5G60970; -.
DR Araport; AT5G60970; -.
DR TAIR; locus:2173557; AT5G60970.
DR eggNOG; ENOG502QS1Y; Eukaryota.
DR HOGENOM; CLU_064607_0_0_1; -.
DR InParanoid; Q9FME3; -.
DR OMA; DENANHH; -.
DR OrthoDB; 995789at2759; -.
DR PhylomeDB; Q9FME3; -.
DR PRO; PR:Q9FME3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FME3; baseline and differential.
DR Genevisible; Q9FME3; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0048366; P:leaf development; IGI:TAIR.
DR GO; GO:0009965; P:leaf morphogenesis; IGI:TAIR.
DR GO; GO:0010150; P:leaf senescence; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0009408; P:response to heat; IDA:TAIR.
DR InterPro; IPR017887; TF_TCP_subgr.
DR InterPro; IPR005333; Transcription_factor_TCP.
DR PANTHER; PTHR31072; PTHR31072; 1.
DR Pfam; PF03634; TCP; 1.
DR PROSITE; PS51369; TCP; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Developmental protein; DNA-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..360
FT /note="Transcription factor TCP5"
FT /id="PRO_0000330779"
FT DOMAIN 63..121
FT /note="TCP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT COILED 3..33
FT /evidence="ECO:0000255"
SQ SEQUENCE 360 AA; 40163 MW; AC8131E4CACD1973 CRC64;
MRSGECDEEE IQAKQERDQN QNHQVNLNHM LQQQQPSSVS SSRQWTSAFR NPRIVRVSRT
FGGKDRHSKV CTVRGLRDRR IRLSVPTAIQ LYDLQDRLGL SQPSKVIDWL LEAAKDDVDK
LPPLQFPHGF NQMYPNLIFG NSGFGESPSS TTSTTFPGTN LGFLENWDLG GSSRTRARLT
DTTTTQRESF DLDKGKWIKN DENSNQDHQG FNTNHQQQFP LTNPYNNTSA YYNLGHLQQS
LDQSGNNVTV AISNVAANNN NNLNLHPPSS SAGDGSQLFF GPTPPAMSSL FPTYPSFLGA
SHHHHVVDGA GHLQLFSSNS NTASQQHMMP GNTSLIRPFH HLMSSNHDTD HHSSDNESDS
