ID   TCPH_VIBCH              Reviewed;         145 AA.
AC   P29489; Q56664; Q9KTR4;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Toxin coregulated pilus biosynthesis protein H;
DE   AltName: Full=TCP pilus biosynthesis protein TcpH;
GN   Name=tcpH; OrderedLocusNames=VC_0827;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Classical Inaba Z17561 / Serotype O1, and El Tor H1 / Serotype O1;
RX   PubMed=8621096; DOI=10.1016/0378-1119(95)00744-x;
RA   Ogierman M.A., Voss E., Meaney C., Faast R., Attridge S.R., Manning P.A.;
RT   "Comparison of the promoter proximal regions of the toxin-co-regulated tcp
RT   gene cluster in classical and El Tor strains of Vibrio cholerae O1.";
RL   Gene 170:9-16(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Involved in TCP pilus biogenesis.
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DR   EMBL; X64098; CAA45454.1; -; Genomic_DNA.
DR   EMBL; X74730; CAA52744.1; -; Genomic_DNA.
DR   EMBL; AE003852; AAF93990.1; -; Genomic_DNA.
DR   PIR; JC4721; JC4721.
DR   PIR; S23263; S23263.
DR   RefSeq; NP_230475.1; NC_002505.1.
DR   AlphaFoldDB; P29489; -.
DR   STRING; 243277.VC_0827; -.
DR   DNASU; 2614494; -.
DR   EnsemblBacteria; AAF93990; AAF93990; VC_0827.
DR   KEGG; vch:VC_0827; -.
DR   PATRIC; fig|243277.26.peg.788; -.
DR   HOGENOM; CLU_155308_0_0_6; -.
DR   OMA; DYSESNV; -.
DR   Proteomes; UP000000584; Chromosome 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..145
FT                   /note="Toxin coregulated pilus biosynthesis protein H"
FT                   /id="PRO_0000072466"
FT   VARIANT         12
FT                   /note="T -> A (in strain: Z17561)"
FT   VARIANT         23
FT                   /note="I -> L (in strain: Z17561)"
FT   VARIANT         95
FT                   /note="Q -> E (in strain: Z17561)"
FT   VARIANT         98
FT                   /note="A -> V (in strain: Z17561)"
FT   VARIANT         122
FT                   /note="L -> Q (in strain: Z17561)"
FT   CONFLICT        129..145
FT                   /note="LVFLSKRFLGSYHEPPR -> WFSCQSD (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   145 AA;  16258 MW;  66620E4576CC9942 CRC64;
     MHKKLKAWGG ATGLFVVALG VTIIALPMRQ KNSHGTMIID GTVTQIFSTY QGNLSNVWLT
     QTDPQGNVVK SWTTRYQTLP DPSSQKLNLI PDYSQSNASR DYNVLSIYQL GKGCFLAFPY
     KLLTAEKMLV FLSKRFLGSY HEPPR