ID   TCPR_VIBC3              Reviewed;         151 AA.
AC   A5F396; C3LYJ7; P29483; Q9JQ07;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Toxin coregulated pilus biosynthesis protein R;
DE   AltName: Full=TCP pilus biosynthesis protein TcpR;
GN   Name=tcpR; OrderedLocusNames=VC0395_A0357, VC395_0848;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11179381; DOI=10.1128/iai.69.3.1947-1952.2001;
RA   Karaolis D.K.R., Lan R., Kaper J.B., Reeves P.R.;
RT   "Comparison of Vibrio cholerae pathogenicity islands in sixth and seventh
RT   pandemic strains.";
RL   Infect. Immun. 69:1947-1952(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Involved in TCP pilus biogenesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
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DR   EMBL; AF325733; AAK20759.1; -; Genomic_DNA.
DR   EMBL; CP000627; ABQ21416.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP08863.1; -; Genomic_DNA.
DR   RefSeq; WP_000200904.1; NZ_JAACZH010000023.1.
DR   AlphaFoldDB; A5F396; -.
DR   STRING; 345073.VC395_0848; -.
DR   EnsemblBacteria; ABQ21416; ABQ21416; VC0395_A0357.
DR   GeneID; 57742475; -.
DR   KEGG; vco:VC0395_A0357; -.
DR   KEGG; vcr:VC395_0848; -.
DR   PATRIC; fig|345073.21.peg.820; -.
DR   HOGENOM; CLU_1730654_0_0_6; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..151
FT                   /note="Toxin coregulated pilus biosynthesis protein R"
FT                   /id="PRO_0000321858"
FT   TRANSMEM        132..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   151 AA;  17764 MW;  63C2B69A3F8DC1A7 CRC64;
     MTSIWLHESD FRYVNLDVER YQKKYRLTLT NGNKYVFIKD KEDISDVNPF IPYILMEEGM
     NNVLVKSDDY KDILIYQGVN IQCLDFLNDN DISVEKLVDF ETVELKADEL NKIKARRLDA
     QLIEDEVKNN KVFIIGFIAI VIISIGVFWL M