ID   TCPR_VIBCH              Reviewed;         151 AA.
AC   P0C6D5; P29483; Q9JQ07;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Toxin coregulated pilus biosynthesis protein R;
DE   AltName: Full=TCP pilus biosynthesis protein TcpR;
GN   Name=tcpR; OrderedLocusNames=VC_0832;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Classical Inaba Z17561 / Serotype O1;
RX   PubMed=8097178; DOI=10.1016/0378-1119(93)90589-u;
RA   Ogierman M.A., Zabihi S., Mourtzios L., Manning P.A.;
RT   "Genetic organization and sequence of the promoter-distal region of the tcp
RT   gene cluster of Vibrio cholerae.";
RL   Gene 126:51-60(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Involved in TCP pilus biogenesis.
CC   -!- INTERACTION:
CC       P0C6D5; P29480: tcpT; NbExp=2; IntAct=EBI-6399872, EBI-6399865;
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
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DR   EMBL; X64098; CAA45459.1; -; Genomic_DNA.
DR   EMBL; AE003852; AAF93995.1; -; Genomic_DNA.
DR   PIR; JN0521; JN0521.
DR   RefSeq; NP_230480.1; NC_002505.1.
DR   RefSeq; WP_000200904.1; NZ_LT906614.1.
DR   AlphaFoldDB; P0C6D5; -.
DR   IntAct; P0C6D5; 1.
DR   STRING; 243277.VC_0832; -.
DR   DNASU; 2614499; -.
DR   EnsemblBacteria; AAF93995; AAF93995; VC_0832.
DR   GeneID; 57742475; -.
DR   KEGG; vch:VC_0832; -.
DR   PATRIC; fig|243277.26.peg.793; -.
DR   HOGENOM; CLU_1730654_0_0_6; -.
DR   BioCyc; VCHO:VC0832-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..151
FT                   /note="Toxin coregulated pilus biosynthesis protein R"
FT                   /id="PRO_0000072469"
FT   TRANSMEM        132..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   151 AA;  17764 MW;  63C2B69A3F8DC1A7 CRC64;
     MTSIWLHESD FRYVNLDVER YQKKYRLTLT NGNKYVFIKD KEDISDVNPF IPYILMEEGM
     NNVLVKSDDY KDILIYQGVN IQCLDFLNDN DISVEKLVDF ETVELKADEL NKIKARRLDA
     QLIEDEVKNN KVFIIGFIAI VIISIGVFWL M