ID   TCSA_LISIN              Reviewed;         357 AA.
AC   Q92BW7;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=CD4+ T-cell-stimulating antigen;
DE   Flags: Precursor;
GN   Name=tcsA; OrderedLocusNames=lin1425;
OS   Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=272626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BMP lipoprotein family. {ECO:0000305}.
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DR   EMBL; AL596168; CAC96656.1; -; Genomic_DNA.
DR   PIR; AH1610; AH1610.
DR   RefSeq; WP_003766833.1; NC_003212.1.
DR   AlphaFoldDB; Q92BW7; -.
DR   SMR; Q92BW7; -.
DR   STRING; 272626.lin1425; -.
DR   EnsemblBacteria; CAC96656; CAC96656; CAC96656.
DR   GeneID; 61170442; -.
DR   KEGG; lin:tcsA; -.
DR   eggNOG; COG1744; Bacteria.
DR   HOGENOM; CLU_038813_0_0_9; -.
DR   OMA; LASMMKR; -.
DR   OrthoDB; 603910at2; -.
DR   Proteomes; UP000002513; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR003760; PnrA-like.
DR   Pfam; PF02608; Bmp; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000305"
FT   CHAIN           23..357
FT                   /note="CD4+ T-cell-stimulating antigen"
FT                   /id="PRO_0000018005"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   357 AA;  38357 MW;  2EDA2AA9820A3FBC CRC64;
     MKKRTFALAL SMIIASGVVL GACGSSSDDK KSGDDKSSKD FTVAMVTDTG GVDDRSFNQS
     AWEGLQKFGK ANDMEKGTDG YNYLQSASEA DYKTNLNTAV RSDYDLIYGI GYKLKDAIEE
     VSKQKPKNQF AIVDDTIDDR DNVVSIGFKD NDGSYLVGVV AGLTTKTNKV GFVGGVKGAV
     IDRFEAGFTA GVKAVNPNAQ IDVQYANDFA KADKGQQIAS SMYSSGVDVI FHAAGGTGNG
     VFAEAKNLKK KDPSRAVWVI GVDRDQWDEG KVTANDGKDY NVTLTSEIKR VDIAVDDLAT
     RTKAGDFPGG TKIEYGLDKD AVGLSEHQDN ISKDVLAKVE EYKQKIVDGD IKVPEKP