ID   TCT1_PHYPO              Reviewed;         217 AA.
AC   O61063;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Tectonin-1;
DE   AltName: Full=Tectonin I;
GN   Name=TECA;
OS   Physarum polycephalum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Myxogastria;
OC   Myxogastromycetidae; Physariida; Physaraceae; Physarum.
OX   NCBI_TaxID=5791;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-21, AND CHARACTERIZATION.
RC   STRAIN=M3;
RX   PubMed=9497393; DOI=10.1074/jbc.273.11.6565;
RA   Huh C.-G., Aldrich J., Mottahedeh J., Kwon H., Johnson C., Marsh R.;
RT   "Cloning and characterization of Physarum polycephalum tectonins.
RT   Homologues of Limulus lectin L-6.";
RL   J. Biol. Chem. 273:6565-6574(1998).
CC   -!- FUNCTION: Probably involved in bacterial recognition. May be a lectin
CC       that function as part of a transmembrane signaling complex during
CC       phagocytosis.
CC   -!- SUBCELLULAR LOCATION: Cell surface. Cytoplasmic vesicle membrane.
CC       Note=Also bound to inner membrane of certain cytoplasmic vesicles.
CC   -!- SIMILARITY: Belongs to the tectonin family. {ECO:0000305}.
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DR   EMBL; AF041455; AAC06200.1; -; mRNA.
DR   AlphaFoldDB; O61063; -.
DR   SMR; O61063; -.
DR   PRIDE; O61063; -.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   InterPro; IPR006624; Beta-propeller_rpt_TECPR.
DR   Pfam; PF19193; Tectonin; 2.
DR   SMART; SM00706; TECPR; 6.
PE   1: Evidence at protein level;
KW   Cytoplasmic vesicle; Direct protein sequencing; Lectin; Membrane; Repeat.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:9497393"
FT   CHAIN           2..217
FT                   /note="Tectonin-1"
FT                   /id="PRO_0000221476"
FT   REPEAT          2..37
FT                   /note="1"
FT   REPEAT          38..74
FT                   /note="2"
FT   REPEAT          75..111
FT                   /note="3"
FT   REPEAT          112..146
FT                   /note="4"
FT   REPEAT          147..182
FT                   /note="5"
FT   REPEAT          183..217
FT                   /note="6"
FT   REGION          2..217
FT                   /note="6 X approximate tandem repeats"
FT   CONFLICT        3
FT                   /note="H -> T (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        7
FT                   /note="H -> W (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        20
FT                   /note="S -> L (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   217 AA;  24825 MW;  88EDA97530AE7716 CRC64;
     MVHWEKHEGE LSVVGVGAGS NDIWGVNHLG HIYHWDGHKW HKVDGELTNI SVGHDGEVWG
     VNKNHNIYRL DRSNNKWTQI PGELVQVSVG SHHHVWGVNH LDHIYKWDHH HNKWDKIDGA
     LTNVSVGKDG TVYGVNRGHQ IYRWDGSKVD LVLGELVQIH VSDAEKIVGV NHLDHIYRLK
     HGKDWEKLDG ELTWVSVGHH GEVWGVNKLH HIYKATL