ID   TCTA_PONAB              Reviewed;         106 AA.
AC   Q5R7E2;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=T-cell leukemia translocation-altered gene protein homolog;
GN   Name=TCTA;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be required for cellular fusion during
CC       osteoclastogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TCTA family. {ECO:0000305}.
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DR   EMBL; CR860176; CAH92318.1; -; mRNA.
DR   RefSeq; NP_001126359.1; NM_001132887.2.
DR   AlphaFoldDB; Q5R7E2; -.
DR   STRING; 9601.ENSPPYP00000015521; -.
DR   GeneID; 100173340; -.
DR   KEGG; pon:100173340; -.
DR   CTD; 6988; -.
DR   eggNOG; ENOG502S6IC; Eukaryota.
DR   HOGENOM; CLU_157357_0_0_1; -.
DR   InParanoid; Q5R7E2; -.
DR   OMA; ESIKTHR; -.
DR   OrthoDB; 1490819at2759; -.
DR   TreeFam; TF330748; -.
DR   Proteomes; UP000001595; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR016560; TCTA.
DR   PANTHER; PTHR32267; PTHR32267; 1.
DR   Pfam; PF15128; T_cell_tran_alt; 1.
DR   PIRSF; PIRSF009935; TCTA; 1.
PE   3: Inferred from homology;
KW   Acetylation; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P57738"
FT   CHAIN           2..106
FT                   /note="T-cell leukemia translocation-altered gene protein
FT                   homolog"
FT                   /id="PRO_0000301680"
FT   TOPO_DOM        2..8
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..43
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        65..106
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   REGION          74..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:P57738"
SQ   SEQUENCE   106 AA;  11582 MW;  6F1BBA8E859A4D13 CRC64;
     MAESWSGQAL QALPATVLGA LGALGSEFLR EWEAQDMRVT LFKLLLLWLV LSLLGIQLAW
     GFYGNTVTGL YHRPGLGGQN GSTPDGSTHF PSWEMAANEP LKTHRE