ID   TCTA_RAT                Reviewed;         106 AA.
AC   Q5XIF1;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=T-cell leukemia translocation-altered gene protein homolog;
GN   Name=Tcta;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be required for cellular fusion during
CC       osteoclastogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TCTA family. {ECO:0000305}.
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DR   EMBL; BC083731; AAH83731.1; -; mRNA.
DR   RefSeq; NP_001014027.1; NM_001014005.1.
DR   AlphaFoldDB; Q5XIF1; -.
DR   STRING; 10116.ENSRNOP00000067537; -.
DR   GlyGen; Q5XIF1; 1 site.
DR   PaxDb; Q5XIF1; -.
DR   GeneID; 306587; -.
DR   KEGG; rno:306587; -.
DR   CTD; 6988; -.
DR   RGD; 1359333; Tcta.
DR   eggNOG; ENOG502S6IC; Eukaryota.
DR   HOGENOM; CLU_157357_0_0_1; -.
DR   InParanoid; Q5XIF1; -.
DR   OMA; ESIKTHR; -.
DR   OrthoDB; 1542196at2759; -.
DR   PhylomeDB; Q5XIF1; -.
DR   ChiTaRS; Tcta; rat.
DR   PRO; PR:Q5XIF1; -.
DR   Proteomes; UP000002494; Chromosome 8.
DR   Bgee; ENSRNOG00000048237; Expressed in heart and 20 other tissues.
DR   Genevisible; Q5XIF1; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; ISO:RGD.
DR   GO; GO:0072675; P:osteoclast fusion; ISO:RGD.
DR   InterPro; IPR016560; TCTA.
DR   PANTHER; PTHR32267; PTHR32267; 1.
DR   Pfam; PF15128; T_cell_tran_alt; 1.
DR   PIRSF; PIRSF009935; TCTA; 1.
PE   3: Inferred from homology;
KW   Acetylation; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P57738"
FT   CHAIN           2..106
FT                   /note="T-cell leukemia translocation-altered gene protein
FT                   homolog"
FT                   /id="PRO_0000301681"
FT   TOPO_DOM        2..8
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..43
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        65..106
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:P57738"
FT   CARBOHYD        80
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   106 AA;  11686 MW;  F7D580D736AE93F4 CRC64;
     MAEPWAGQFL QALPATVLGA LGTLGSEFLR EWETQDMRVT LFKLLLLWLV LSLLGIQLAW
     GFYGNTVTGL YHRPGLGGQN GSTPDGSTHF PSWEMAANEA LKTHRE