ID   TCTD_SALTS              Reviewed;         224 AA.
AC   E1WA34; P22104;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Transcriptional regulatory protein TctD;
GN   Name=tctD; OrderedLocusNames=SL1344_2769;
OS   Salmonella typhimurium (strain SL1344).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=216597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=11083839; DOI=10.1128/iai.68.12.7126-7131.2000;
RA   Valdivia R.H., Cirillo D.M., Lee A.K., Bouley D.M., Falkow S.;
RT   "mig-14 is a horizontally acquired, host-induced gene required for
RT   Salmonella enterica lethal infection in the murine model of typhoid
RT   fever.";
RL   Infect. Immun. 68:7126-7131(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=22538806; DOI=10.1073/pnas.1201061109;
RA   Kroger C., Dillon S.C., Cameron A.D., Papenfort K., Sivasankaran S.K.,
RA   Hokamp K., Chao Y., Sittka A., Hebrard M., Handler K., Colgan A.,
RA   Leekitcharoenphon P., Langridge G.C., Lohan A.J., Loftus B., Lucchini S.,
RA   Ussery D.W., Dorman C.J., Thomson N.R., Vogel J., Hinton J.C.;
RT   "The transcriptional landscape and small RNAs of Salmonella enterica
RT   serovar Typhimurium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:E1277-E1286(2012).
CC   -!- FUNCTION: Transcriptional activator of the tctI tricarboxylate
CC       transport system operon. {ECO:0000250}.
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DR   EMBL; AF020810; AAG31204.1; -; Genomic_DNA.
DR   EMBL; FQ312003; CBW18867.1; -; Genomic_DNA.
DR   RefSeq; WP_001237934.1; NZ_QASL01000009.1.
DR   AlphaFoldDB; E1WA34; -.
DR   SMR; E1WA34; -.
DR   EnsemblBacteria; CBW18867; CBW18867; SL1344_2769.
DR   KEGG; sey:SL1344_2769; -.
DR   PATRIC; fig|216597.6.peg.3080; -.
DR   HOGENOM; CLU_000445_30_1_6; -.
DR   OMA; RSFIVIN; -.
DR   BioCyc; SENT216597:SL1344_RS14415-MON; -.
DR   Proteomes; UP000008962; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00448; REC; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..224
FT                   /note="Transcriptional regulatory protein TctD"
FT                   /id="PRO_0000405428"
FT   DOMAIN          2..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        121..219
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT   MOD_RES         51
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   224 AA;  25407 MW;  DFB6D1DE013DF8CA CRC64;
     MRLLLAEDNR ELAHWLEKAL VQNGFAVDCV FDGLAADHLL HSEMYALAVL DINMPGMDGL
     EVVQRLRKRG QTLPVLLLTA RSAVADRVKG LNVGADDYLP KPFELEELDA RLRALLRRSA
     GQVHEVQQLG ELIFHDEGYF LLQGQPLALT PREQALLTVL MYRRTRPVSR QQLFEQVFSL
     NDEVSPESIE LYIHRLRKKL QGSDVRITTL RGLGYVLERG DEVG