ID   TCTP1_DICDI             Reviewed;         174 AA.
AC   Q54RX6;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Translationally-controlled tumor protein homolog 1;
DE            Short=TCTP 1;
GN   ORFNames=DDB_G0282853;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AAFI02000047; EAL66006.1; -; Genomic_DNA.
DR   RefSeq; XP_639361.1; XM_634269.1.
DR   AlphaFoldDB; Q54RX6; -.
DR   SMR; Q54RX6; -.
DR   STRING; 44689.DDB0305046; -.
DR   PaxDb; Q54RX6; -.
DR   EnsemblProtists; EAL66006; EAL66006; DDB_G0282853.
DR   GeneID; 8623801; -.
DR   KEGG; ddi:DDB_G0282853; -.
DR   dictyBase; DDB_G0282853; tpt1.
DR   eggNOG; KOG1727; Eukaryota.
DR   HOGENOM; CLU_095877_1_0_1; -.
DR   InParanoid; Q54RX6; -.
DR   OMA; IVYEADC; -.
DR   PhylomeDB; Q54RX6; -.
DR   PRO; PR:Q54RX6; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; TAS:dictyBase.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0019954; P:asexual reproduction; IMP:dictyBase.
DR   GO; GO:0030154; P:cell differentiation; IMP:dictyBase.
DR   GO; GO:0044351; P:macropinocytosis; IMP:dictyBase.
DR   GO; GO:0030587; P:sorocarp development; IMP:dictyBase.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   3: Inferred from homology;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..174
FT                   /note="Translationally-controlled tumor protein homolog 1"
FT                   /id="PRO_0000328127"
FT   DOMAIN          1..174
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   174 AA;  19541 MW;  C279C140FE338634 CRC64;
     MRVFKDIVGY SHDELCSDAY PMTEINNGLI YEVQAKMVTI DLDVKVNTGA NAASEETEED
     EGVDNAGSKQ VINVVDAMRL VETSFDKKSY TGYIKAYMKE VLAKLADNNP SRVDAFKKDA
     ADFVKSVLGK FDEYKFYTGE NMDADGHVAL MYYKPGEVDP IFLYFKDGLE SVKY