ID   TCTP2_DICDI             Reviewed;         194 AA.
AC   Q54RX1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Translationally-controlled tumor protein homolog 2;
DE            Short=TCTP 2;
GN   ORFNames=DDB_G0282861;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AAFI02000047; EAL66010.1; -; Genomic_DNA.
DR   RefSeq; XP_639366.1; XM_634274.1.
DR   AlphaFoldDB; Q54RX1; -.
DR   SMR; Q54RX1; -.
DR   STRING; 44689.DDB0305047; -.
DR   PaxDb; Q54RX1; -.
DR   EnsemblProtists; EAL66010; EAL66010; DDB_G0282861.
DR   GeneID; 8623806; -.
DR   KEGG; ddi:DDB_G0282861; -.
DR   dictyBase; DDB_G0282861; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   HOGENOM; CLU_1404821_0_0_1; -.
DR   InParanoid; Q54RX1; -.
DR   PhylomeDB; Q54RX1; -.
DR   PRO; PR:Q54RX1; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   3: Inferred from homology;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..194
FT                   /note="Translationally-controlled tumor protein homolog 2"
FT                   /id="PRO_0000328126"
FT   DOMAIN          1..194
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   194 AA;  22069 MW;  4A90CA0BDFB7ABBA CRC64;
     MKLYKDLIGN SHDDLLTDRY EIKVGDVTFE VKTKMITKDL NVVVNNNSLG GSISTTVDNN
     NSITLSTNLE DEFENVEAAG TFQINNLVEQ LRLVETSFDK KSYLAYMKLY IKDLINHIKQ
     QPSNSDNEKI EHIQKGIQSF VKTMMDGENF KKYSFFTGSS MDANGLVALM YYKDDDPTTP
     TFVFIKYGLL QVDV