ID   TCTP8_HUMAN             Reviewed;         139 AA.
AC   Q9HAU6;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2013, sequence version 2.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Putative translationally-controlled tumor protein-like protein TPT1P8;
DE   AltName: Full=Putative apoptosis inhibitor FKSG2;
GN   Name=TPT1P8; ORFNames=FKSG2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Wang Y.-G.;
RT   "Cloning and characterization of FKSG2, a novel inhibitor of apoptosis.";
RL   Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG17927.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AF300871; AAG17927.1; ALT_FRAME; mRNA.
DR   EMBL; AC138136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q9HAU6; -.
DR   SMR; Q9HAU6; -.
DR   iPTMnet; Q9HAU6; -.
DR   PhosphoSitePlus; Q9HAU6; -.
DR   BioMuta; HGNC:24088; -.
DR   DMDM; 527504045; -.
DR   jPOST; Q9HAU6; -.
DR   MassIVE; Q9HAU6; -.
DR   PeptideAtlas; Q9HAU6; -.
DR   PRIDE; Q9HAU6; -.
DR   ProteomicsDB; 81442; -.
DR   GeneCards; TPT1P8; -.
DR   HGNC; HGNC:24088; TPT1P8.
DR   neXtProt; NX_Q9HAU6; -.
DR   InParanoid; Q9HAU6; -.
DR   PathwayCommons; Q9HAU6; -.
DR   Pharos; Q9HAU6; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q9HAU6; protein.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   5: Uncertain;
KW   Apoptosis; Reference proteome.
FT   CHAIN           1..139
FT                   /note="Putative translationally-controlled tumor protein-
FT                   like protein TPT1P8"
FT                   /id="PRO_0000211312"
FT   DOMAIN          1..139
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   REGION          40..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   139 AA;  15994 MW;  E58F715ED5C64DFB CRC64;
     MIIFQDLISH NEMFSDIYKI WEITNGLCLE VEQKMLSKTT GNTDDSLIGR NSSSESTEDE
     VTESTIITSV DIVTNHHLQE SIFTKEAYKK YIKDYMKSIN EKLEEQRPER VKLFITGMKN
     KSSTSLLIFK TTSSLLVKT