ID   TCTP_BOVIN              Reviewed;         172 AA.
AC   Q5E984; Q3SX12; Q862G3; Q862H4; Q862N1; Q862X2; Q862Y4;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Translationally-controlled tumor protein;
DE            Short=TCTP;
GN   Name=TPT1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-155.
RX   PubMed=12658628; DOI=10.1002/mrd.10292;
RA   Ishiwata H., Katsuma S., Kizaki K., Patel O.V., Nakano H., Takahashi T.,
RA   Imai K., Hirasawa A., Shiojima S., Ikawa H., Suzuki Y., Tsujimoto G.,
RA   Izaike Y., Todoroki J., Hashizume K.;
RT   "Characterization of gene expression profiles in early bovine pregnancy
RT   using a custom cDNA microarray.";
RL   Mol. Reprod. Dev. 65:9-18(2003).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with STEAP3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC56439.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=BAC56506.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; BT021036; AAX09053.1; -; mRNA.
DR   EMBL; BC104562; AAI04563.1; -; mRNA.
DR   EMBL; AB098949; BAC56439.1; ALT_FRAME; mRNA.
DR   EMBL; AB099016; BAC56506.1; ALT_FRAME; mRNA.
DR   EMBL; AB099031; BAC56521.1; -; mRNA.
DR   RefSeq; NP_001014410.1; NM_001014388.1.
DR   AlphaFoldDB; Q5E984; -.
DR   BMRB; Q5E984; -.
DR   SMR; Q5E984; -.
DR   STRING; 9913.ENSBTAP00000013402; -.
DR   PaxDb; Q5E984; -.
DR   PeptideAtlas; Q5E984; -.
DR   PRIDE; Q5E984; -.
DR   GeneID; 326599; -.
DR   KEGG; bta:326599; -.
DR   CTD; 7178; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   HOGENOM; CLU_095877_0_1_1; -.
DR   InParanoid; Q5E984; -.
DR   OrthoDB; 1439384at2759; -.
DR   TreeFam; TF300238; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:AgBase.
DR   GO; GO:0005881; C:cytoplasmic microtubule; ISS:AgBase.
DR   GO; GO:0005615; C:extracellular space; ISS:AgBase.
DR   GO; GO:0005771; C:multivesicular body; ISS:AgBase.
DR   GO; GO:0000922; C:spindle pole; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:AgBase.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm; Phosphoprotein; Reference proteome.
FT   CHAIN           1..172
FT                   /note="Translationally-controlled tumor protein"
FT                   /id="PRO_0000211267"
FT   DOMAIN          1..172
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   MOD_RES         46
FT                   /note="Phosphoserine; by PLK1"
FT                   /evidence="ECO:0000250|UniProtKB:P13693"
FT   MOD_RES         53
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P13693"
FT   MOD_RES         64
FT                   /note="Phosphoserine; by PLK1"
FT                   /evidence="ECO:0000250|UniProtKB:P13693"
SQ   SEQUENCE   172 AA;  19581 MW;  ECDE3985802DFFD0 CRC64;
     MIIYRDLISH DEMFSDIYKI REVADGLCLE VEGKMVSRTE GNIDDSLIGG NASAEGPEGE
     GTESTVITGV DIVMNHHLQE TSFTKEAYKK YIKDYMKSIK GKLEEQRPER VKPFMTGAAE
     QIKHILANFK NYQFFIGENM NPDGMVALLD YREDGVTPYM IFFKDGLEME KC