ID   TCTP_BRUMA              Reviewed;         181 AA.
AC   P90697;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
DE   AltName: Full=TPH-1;
OS   Brugia malayi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9233676; DOI=10.1016/s0166-6851(97)00050-9;
RA   Gregory W.F., Blaxter M.L., Maizels R.M.;
RT   "Differentially expressed, abundant trans-spliced cDNAs from larval Brugia
RT   malayi.";
RL   Mol. Biochem. Parasitol. 87:85-95(1997).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; U80971; AAC47622.1; -; mRNA.
DR   AlphaFoldDB; P90697; -.
DR   SMR; P90697; -.
DR   STRING; 6279.P90697; -.
DR   Proteomes; UP000006672; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..181
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211280"
FT   DOMAIN          1..181
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   181 AA;  20764 MW;  C05F62685E8D0304 CRC64;
     MLIFKDAFTD DELASDSFPM KLVDGLIWEF KGRQVVRREG EIQLAGANPS AEGEDGDEGS
     EECVERGIDF VLNHRLQEMN CYEDLVTFKS YCKSFMKKVV ELMQKNGKSE AEISEFKRKI
     PAWVVSLLSK DRFKQLQFFI GERMAEGQGE GQVAVVEYRD EEDGEVPYLM LVKEALIEEK
     Q