ID   TCTP_CANGA              Reviewed;         167 AA.
AC   Q6FKB6;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   OrderedLocusNames=CAGL0L12870g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in protein synthesis. Involved in microtubule
CC       stabilization (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; CR380958; CAG62302.1; -; Genomic_DNA.
DR   RefSeq; XP_449328.1; XM_449328.1.
DR   AlphaFoldDB; Q6FKB6; -.
DR   SMR; Q6FKB6; -.
DR   STRING; 5478.XP_449328.1; -.
DR   PRIDE; Q6FKB6; -.
DR   EnsemblFungi; CAG62302; CAG62302; CAGL0L12870g.
DR   GeneID; 2890578; -.
DR   KEGG; cgr:CAGL0L12870g; -.
DR   CGD; CAL0136162; CAGL0L12870g.
DR   VEuPathDB; FungiDB:CAGL0L12870g; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   HOGENOM; CLU_095877_0_0_1; -.
DR   InParanoid; Q6FKB6; -.
DR   OMA; IVYEADC; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IEA:EnsemblFungi.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblFungi.
DR   GO; GO:0002181; P:cytoplasmic translation; IEA:EnsemblFungi.
DR   GO; GO:0010507; P:negative regulation of autophagy; IEA:EnsemblFungi.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:EnsemblFungi.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Microtubule; Protein biosynthesis;
KW   Reference proteome.
FT   CHAIN           1..167
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000252320"
FT   DOMAIN          1..167
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   167 AA;  18681 MW;  B7B12E69487FE580 CRC64;
     MIIYKDIFSG DELLSDAYDI NEVDGVIYEA DCAMVKVGGD NIDIGANPST EDGEDDVEDG
     TEVVNNVVHS FRLQPTGFDK KSFLTYIKGY MKAVKAKLQE KNPDAIPTFE KGAQVYVKKV
     IGSFKDWEFF TGESMDPDAM VVMLNYREDG TTPFVAIWKH GIDEEKI