位置:首页 > 蛋白库 > TCTP_CROAD
TCTP_CROAD
ID   TCTP_CROAD              Reviewed;         172 AA.
AC   J3SFJ3;
DT   11-JUN-2014, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2012, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
OS   Crotalus adamanteus (Eastern diamondback rattlesnake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX   NCBI_TaxID=8729;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=23025625; DOI=10.1186/1471-2164-13-312;
RA   Rokyta D.R., Lemmon A.R., Margres M.J., Aronow K.;
RT   "The venom-gland transcriptome of the eastern diamondback rattlesnake
RT   (Crotalus adamanteus).";
RL   BMC Genomics 13:312-312(2012).
CC   -!- FUNCTION: Venom protein that causes edema, enhances vascular
CC       permeability and is likely related to the inflammatory activity of the
CC       venom. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- MISCELLANEOUS: Secretion of this protein from cells may proceed via an
CC       ER/Golgi-independent pathway, probably mediated by secreted vesicles
CC       called exosomes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JU176353; AFJ51876.1; -; mRNA.
DR   AlphaFoldDB; J3SFJ3; -.
DR   SMR; J3SFJ3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Secreted.
FT   CHAIN           1..172
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000429459"
FT   DOMAIN          1..172
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   172 AA;  19433 MW;  5FC5CB782045AC3B CRC64;
     MIIYRDCISQ DEMFSDIYKI TEVANGLCLE VEGKMVSRKE GEIDDALIGG NASAEGPEGD
     GTEATVITGV DIVMNHHLQE TSFTKESYKK YIKDYMKSIK ARLEETKPER VKPFMTGAAE
     QVKHILGNFK NYQFFVGENM NPDGMVGLLD FREDGVTPYM IFFKDGLEME KC
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024