ID   TCTP_CRYNJ              Reviewed;         167 AA.
AC   P0CR82; Q55I87; Q5K7S2;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   OrderedLocusNames=CNM01460;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Involved in protein synthesis. Involved in microtubule
CC       stabilization (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AE017353; AAW46936.1; -; Genomic_DNA.
DR   RefSeq; XP_568453.1; XM_568453.1.
DR   AlphaFoldDB; P0CR82; -.
DR   SMR; P0CR82; -.
DR   STRING; 5207.AAW46936; -.
DR   PaxDb; P0CR82; -.
DR   PRIDE; P0CR82; -.
DR   EnsemblFungi; AAW46936; AAW46936; CNM01460.
DR   GeneID; 3255250; -.
DR   KEGG; cne:CNM01460; -.
DR   VEuPathDB; FungiDB:CNM01460; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   HOGENOM; CLU_095877_0_0_1; -.
DR   InParanoid; P0CR82; -.
DR   OMA; IVYEADC; -.
DR   OrthoDB; 1439384at2759; -.
DR   Proteomes; UP000002149; Chromosome 13.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Microtubule; Protein biosynthesis;
KW   Reference proteome.
FT   CHAIN           1..167
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000252321"
FT   DOMAIN          1..167
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   167 AA;  18763 MW;  C823C76B56DAA526 CRC64;
     MLIYQDVLTG DEMISDAFPI KEIGDIAYEV DCANIIIKEG DVDIGGNPSA EEAAEALEEG
     AQQVNNVVHS FRLQSTSFDK KSYLTYLKGY MKAIKSKLQE SNPDRVAAFE KGAQDFAKKI
     VANFKDYEFY IGESMNPDGM VCLLNYREDG VTPYFTMWKD GLKEIKI