ID   TCTP_DANRE              Reviewed;         171 AA.
AC   Q9DGK4; Q7ZUG2;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=tpt1; Synonyms=tct1, tctp;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Good P.J.;
RT   "The zebrafish gene encoding the translationally-controlled tumor protein 1
RT   (tct1) is ubiquitously expressed during early development.";
RL   Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AF288217; AAF99708.1; -; mRNA.
DR   EMBL; BC049059; AAH49059.1; -; mRNA.
DR   RefSeq; NP_937783.1; NM_198140.1.
DR   AlphaFoldDB; Q9DGK4; -.
DR   SMR; Q9DGK4; -.
DR   STRING; 7955.ENSDARP00000110449; -.
DR   PaxDb; Q9DGK4; -.
DR   DNASU; 30723; -.
DR   Ensembl; ENSDART00000102111; ENSDARP00000092887; ENSDARG00000092693.
DR   GeneID; 30723; -.
DR   KEGG; dre:30723; -.
DR   CTD; 7178; -.
DR   ZFIN; ZDB-GENE-990603-10; tpt1.
DR   eggNOG; KOG1727; Eukaryota.
DR   GeneTree; ENSGT00390000006051; -.
DR   HOGENOM; CLU_095877_0_1_1; -.
DR   InParanoid; Q9DGK4; -.
DR   OMA; TPYMISF; -.
DR   OrthoDB; 1439384at2759; -.
DR   PhylomeDB; Q9DGK4; -.
DR   TreeFam; TF300238; -.
DR   PRO; PR:Q9DGK4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 1.
DR   Bgee; ENSDARG00000092693; Expressed in gastrula and 25 other tissues.
DR   ExpressionAtlas; Q9DGK4; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..171
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211274"
FT   DOMAIN          1..171
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   CONFLICT        161
FT                   /note="F -> S (in Ref. 2; AAH49059)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   171 AA;  19025 MW;  2D56CDCDAA74DE5C CRC64;
     MIIYKDIITG DEMFSDIYKI KESENGMMLE VEGKMITRAE GDIDDALIGG NASAEVADEG
     CDSTSVSGVD IVLNHKLQET SYDKKSYTAY IKDYMKAVKA KLQESAPNRV DPFMANAPAE
     VKKILGNIKN FQFFTGESMN PDGMIGLLDF REDGVTPYMI FFKDGLEIEK C