ID   TCTP_GRARO              Reviewed;         173 AA.
AC   M5B4R7;
DT   11-JUN-2014, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2013, sequence version 1.
DT   25-MAY-2022, entry version 19.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=GTx-TCTP1;
OS   Grammostola rosea (Chilean rose tarantula) (Grammostola spatulata).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Mygalomorphae; Theraphosidae; Grammostola.
OX   NCBI_TaxID=432528;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RA   Kimura T., Kubo T.;
RT   "Grammostola spatulata venom gland cDNA.";
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Venom protein that causes edema, enhances vascular
CC       permeability and is likely related to the inflammatory activity of the
CC       venom. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- MISCELLANEOUS: Secretion of this protein from cells may proceed via an
CC       ER/Golgi-independent pathway, probably mediated by secreted vesicles
CC       called exosomes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AB201040; BAN13536.1; -; mRNA.
DR   AlphaFoldDB; M5B4R7; -.
DR   SMR; M5B4R7; -.
DR   ArachnoServer; AS001840; TCTP1-1-Grammostola rosea.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Secreted.
FT   CHAIN           1..173
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000429458"
FT   DOMAIN          1..173
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   173 AA;  19618 MW;  AC01D27CE1BB52BF CRC64;
     MIIFKDMITG DEMFTDSSKY KVVDDCILEV ECRHVTRRMG DIQLEGANPS QEEADEGTDE
     VTESGLDLVL NQRLVETGFS KSDYKNYLKT YTKALQDKWK EVGMSDSQMA EAKTKFTEAV
     KKVLPKVGDL QFFMGESSNP DGLVALLEYR ENSDGTETPV MMFFKHGLEE EKV