ID   TCTP_HEVBR              Reviewed;         168 AA.
AC   Q9ZSW9; Q2MJR9;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=TCTP;
OS   Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Micrandreae;
OC   Hevea.
OX   NCBI_TaxID=3981;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Latex;
RA   Shin D.H., Han K.-H.;
RT   "A Hevea brasiliensis homolog of translationally controlled tumor protein
RT   (HevTCTP) is expressed abundantly in latex.";
RL   (er) Plant Gene Register PGR99-005(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Latex;
RA   Venkatachalam P., Raghothama K.G., Thulaseedharan A.;
RT   "Cloning and nucleotide sequence analysis of translationally controlled
RT   tumor induce protein (TCTP) gene associated with TPD syndrome in rubber
RT   tree (Hevea brasiliensis).";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AF091455; AAD10032.1; -; mRNA.
DR   EMBL; DQ323740; ABC55649.1; -; mRNA.
DR   AlphaFoldDB; Q9ZSW9; -.
DR   SMR; Q9ZSW9; -.
DR   PRIDE; Q9ZSW9; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm.
FT   CHAIN           1..168
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211301"
FT   DOMAIN          1..168
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   CONFLICT        32
FT                   /note="E -> V (in Ref. 2; ABC55649)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        101
FT                   /note="K -> M (in Ref. 2; ABC55649)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        149
FT                   /note="G -> E (in Ref. 2; ABC55649)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   168 AA;  19039 MW;  71C7B1310F64A385 CRC64;
     MLVYQDLLTG DELLSDSFPY KEIHNGILWE VEGKWVVQGA VDVDIGANPS AEGADEDEGV
     DDQAVKVVDI VDTFRLQEQP AFDKKQFVTY MKRFIKLLTP KLDEEKQESF KKNIEGATKF
     LLSKLSDLQF FVGESMHDDG SLVFAYYRGG ATDPTFLYFA YALKEVKC