ID   TCTP_IXOSC              Reviewed;         173 AA.
AC   Q4PLZ3;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=Tctp;
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=IS-6-12-J-cluster-559; TISSUE=Salivary gland;
RX   PubMed=16431279; DOI=10.1016/j.ibmb.2005.11.005;
RA   Ribeiro J.M.C., Alarcon-Chaidez F., Francischetti I.M.B., Mans B.J.,
RA   Mather T.N., Valenzuela J.G., Wikel S.K.;
RT   "An annotated catalog of salivary gland transcripts from Ixodes scapularis
RT   ticks.";
RL   Insect Biochem. Mol. Biol. 36:111-129(2006).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; DQ066335; AAY66972.1; -; mRNA.
DR   AlphaFoldDB; Q4PLZ3; -.
DR   SMR; Q4PLZ3; -.
DR   EnsemblMetazoa; ISCI024497-RA; ISCI024497-PA; ISCI024497.
DR   VEuPathDB; VectorBase:ISCI024497; -.
DR   VEuPathDB; VectorBase:ISCW024497; -.
DR   HOGENOM; CLU_1612701_0_0_1; -.
DR   OrthoDB; 1439384at2759; -.
DR   Proteomes; UP000001555; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..173
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211284"
FT   DOMAIN          1..173
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   173 AA;  19428 MW;  7C86A3570387B2E5 CRC64;
     MLLFKDILTG DEMFTDSVKY KLVDDCIFEI ECEHVTRKVG EVALDGANPS AEEVEEGTEE
     GTESGLDLVL NMRLVETGFS KTDYKNYLKT YTKALMDKWK EDGKSEAEVN EAKSKLTEAV
     KKVLPRIGDM QFFLGESSNP DGIVALLEYR PNKSGGETPV VMFFKHGLLE EKQ