ID   TCTP_LUMRU              Reviewed;         167 AA.
AC   O18477;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=TCTP;
OS   Lumbricus rubellus (Humus earthworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC   Oligochaeta; Crassiclitellata; Lumbricina; Lumbricidae; Lumbricinae;
OC   Lumbricus.
OX   NCBI_TaxID=35632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9655922; DOI=10.1016/s0167-4781(98)00077-3;
RA   Stuerzenbaum S.R., Kille P., Morgan A.J.;
RT   "Identification of heavy metal induced changes in the expression patterns
RT   of the translationally controlled tumour protein (TCTP) in the earthworm
RT   Lumbricus rubellus.";
RL   Biochim. Biophys. Acta 1398:294-304(1998).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- INDUCTION: By cadmium.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; Y08158; CAA69350.1; -; mRNA.
DR   AlphaFoldDB; O18477; -.
DR   SMR; O18477; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm.
FT   CHAIN           1..167
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211288"
FT   DOMAIN          1..167
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   167 AA;  18837 MW;  BAC941FB8076A24C CRC64;
     MIIFKDVFPG VELFSDSFPV SLVNETVYKV KGKLRTDTFA IDDKAIGGNA SAEGGEEGTD
     AASKQGVDIV MNSRLVEYAL SKKDYMTHIK SYMKSVKDKL QETKPADSEL FQKNVQPFIK
     EVLNDFKEYQ LFCGESMGPE GMLALMKWDG ETPYMFFFKH GLDEEKV