ID   TCTP_MEDSA              Reviewed;         167 AA.
AC   P28014; Q40370;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=TCTP;
OS   Medicago sativa (Alfalfa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX   NCBI_TaxID=3879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. RA3; TISSUE=Callus;
RA   Scecsi J., Nemeth K., Dudits D., Gyorgyey J.;
RL   Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 11-167.
RC   STRAIN=cv. RA3;
RX   PubMed=1623194; DOI=10.1007/bf00023399;
RA   Pay A., Heberle-Bors E., Hirt H.;
RT   "An alfalfa cDNA encodes a protein with homology to translationally
RT   controlled human tumor protein.";
RL   Plant Mol. Biol. 19:501-503(1992).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X98618; CAA67207.1; -; mRNA.
DR   EMBL; X63872; CAA45349.1; -; mRNA.
DR   PIR; S22489; S22489.
DR   PIR; T09686; T09686.
DR   AlphaFoldDB; P28014; -.
DR   SMR; P28014; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm.
FT   CHAIN           1..167
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211303"
FT   DOMAIN          1..167
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   CONFLICT        122
FT                   /note="C -> G (in Ref. 2; CAA45349)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   167 AA;  18941 MW;  9A9D663D0800E5FE CRC64;
     MLVYQDLLTG DELLSDSYPY KEIENGMLWE VEGKWVTKGV VEVDIGANAS AEGGEDEGVD
     DTAVKVVDIV DVFRLQEQPA FDKKQFLGFV KRYIKLLTPK LDAEKQELFK KHIEGATKYL
     LCKLKDLQFF VGESMHDDGS LVFAYYKDGA ADPTFLYFAY ALKEIKC