ID   TCTP_MICFL              Reviewed;         171 AA.
AC   U3EQ60;
DT   11-JUN-2014, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2013, sequence version 1.
DT   25-MAY-2022, entry version 17.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
OS   Micrurus fulvius (Eastern coral snake) (Coluber fulvius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Micrurus.
OX   NCBI_TaxID=8637;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=23915248; DOI=10.1186/1471-2164-14-531;
RA   Margres M.J., Aronow K., Loyacano J., Rokyta D.R.;
RT   "The venom-gland transcriptome of the eastern coral snake (Micrurus
RT   fulvius) reveals high venom complexity in the intragenomic evolution of
RT   venoms.";
RL   BMC Genomics 14:531-531(2013).
CC   -!- FUNCTION: Venom protein that causes edema, enhances vascular
CC       permeability and is likely related to the inflammatory activity of the
CC       venom. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- MISCELLANEOUS: Secretion of this protein from cells may proceed via an
CC       ER/Golgi-independent pathway, probably mediated by secreted vesicles
CC       called exosomes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; GAEP01001768; JAB53053.1; -; mRNA.
DR   AlphaFoldDB; U3EQ60; -.
DR   SMR; U3EQ60; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Secreted.
FT   CHAIN           1..171
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000429461"
FT   DOMAIN          1..171
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   171 AA;  19408 MW;  393D4B76E8D5E7E0 CRC64;
     MIIYRDCISQ DEMFSDIYKI TEVANGLCLE VEGKMVSRKE GEIDEALIGG NASADGPEDC
     TEATVITGVD IVMNHHLQET SFTKESYKKY IKDYMKSIKA RLEESKPERV KPFMTGAAEQ
     VKHILGNFKN YQFFVGENMN PDGMVGLLDF REDGVTPYMI FFKDGLEMEK C