ID   TCTP_PANTR              Reviewed;         172 AA.
AC   A5A6K2;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Translationally-controlled tumor protein;
DE            Short=TCTP;
GN   Name=TPT1;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Brain;
RX   PubMed=17574350; DOI=10.1016/j.gene.2007.04.013;
RA   Sakate R., Suto Y., Imanishi T., Tanoue T., Hida M., Hayasaka I.,
RA   Kusuda J., Gojobori T., Hashimoto K., Hirai M.;
RT   "Mapping of chimpanzee full-length cDNAs onto the human genome unveils
RT   large potential divergence of the transcriptome.";
RL   Gene 399:1-10(2007).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with STEAP3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AB222130; BAF62375.1; -; mRNA.
DR   RefSeq; NP_001092016.1; NM_001098546.2.
DR   RefSeq; XP_016776922.1; XM_016921433.1.
DR   AlphaFoldDB; A5A6K2; -.
DR   BMRB; A5A6K2; -.
DR   SMR; A5A6K2; -.
DR   STRING; 9598.ENSPTRP00000060060; -.
DR   PaxDb; A5A6K2; -.
DR   Ensembl; ENSPTRT00000031134; ENSPTRP00000060060; ENSPTRG00000034210.
DR   Ensembl; ENSPTRT00000095548; ENSPTRP00000091361; ENSPTRG00000042843.
DR   GeneID; 452575; -.
DR   KEGG; ptr:452575; -.
DR   CTD; 7178; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   GeneTree; ENSGT00390000006051; -.
DR   HOGENOM; CLU_095877_0_1_1; -.
DR   InParanoid; A5A6K2; -.
DR   OMA; IVYEADC; -.
DR   OrthoDB; 1439384at2759; -.
DR   TreeFam; TF300238; -.
DR   Proteomes; UP000002277; Chromosome 13.
DR   Proteomes; UP000002277; Chromosome 5.
DR   Bgee; ENSPTRG00000034210; Expressed in Brodmann (1909) area 10 and 18 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cytoplasm; Phosphoprotein; Reference proteome.
FT   CHAIN           1..172
FT                   /note="Translationally-controlled tumor protein"
FT                   /id="PRO_0000295285"
FT   DOMAIN          1..172
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   MOD_RES         46
FT                   /note="Phosphoserine; by PLK1"
FT                   /evidence="ECO:0000250|UniProtKB:P13693"
FT   MOD_RES         53
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P13693"
FT   MOD_RES         64
FT                   /note="Phosphoserine; by PLK1"
FT                   /evidence="ECO:0000250|UniProtKB:P13693"
SQ   SEQUENCE   172 AA;  19595 MW;  BD31399B71CA62F9 CRC64;
     MIIYRDLISH DEMFSDIYKI REIADGLCLE VEGKMVSRTE GNIDDSLIGG NASAEGPEGE
     GTESTVITGV DIVMNHHLQE TSFTKEAYKK YIKDYMKSIK GKLEEQRPER VKPFMTGAAE
     QIKHILANFK NYQFFIGENM NPDGMVALLD YREDGVTPYM IFFKDGLEME KC