TCTP_PLABA
ID TCTP_PLABA Reviewed; 171 AA.
AC Q4YZC6;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Translationally-controlled tumor protein homolog;
DE Short=TCTP;
GN Name=TCTP; ORFNames=PB000913.01.0;
OS Plasmodium berghei (strain Anka).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=5823;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANKA;
RX PubMed=15637271; DOI=10.1126/science.1103717;
RA Hall N., Karras M., Raine J.D., Carlton J.M., Kooij T.W.A., Berriman M.,
RA Florens L., Janssen C.S., Pain A., Christophides G.K., James K.,
RA Rutherford K., Harris B., Harris D., Churcher C.M., Quail M.A., Ormond D.,
RA Doggett J., Trueman H.E., Mendoza J., Bidwell S.L., Rajandream M.A.,
RA Carucci D.J., Yates J.R. III, Kafatos F.C., Janse C.J., Barrell B.G.,
RA Turner C.M.R., Waters A.P., Sinden R.S.;
RT "A comprehensive survey of the Plasmodium life cycle by genomic,
RT transcriptomic, and proteomic analyses.";
RL Science 307:82-86(2005).
CC -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC ProRule:PRU01133}.
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DR EMBL; CAAI01001543; CAH96616.1; -; Genomic_DNA.
DR RefSeq; XP_679535.1; XM_674443.1.
DR AlphaFoldDB; Q4YZC6; -.
DR SMR; Q4YZC6; -.
DR STRING; 5821.PBANKA_111050; -.
DR VEuPathDB; PlasmoDB:PBANKA_1110500; -.
DR eggNOG; KOG1727; Eukaryota.
DR HOGENOM; CLU_095877_0_1_1; -.
DR InParanoid; Q4YZC6; -.
DR OMA; IVYEADC; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 2.170.150.10; -; 1.
DR InterPro; IPR011057; Mss4-like_sf.
DR InterPro; IPR011323; Mss4/transl-control_tumour.
DR InterPro; IPR034737; TCTP.
DR InterPro; IPR018103; Translation_control_tumour_CS.
DR InterPro; IPR018105; Translational_control_tumour_p.
DR PANTHER; PTHR11991; PTHR11991; 1.
DR Pfam; PF00838; TCTP; 1.
DR PRINTS; PR01653; TCTPROTEIN.
DR SUPFAM; SSF51316; SSF51316; 1.
DR PROSITE; PS01003; TCTP_2; 1.
DR PROSITE; PS51797; TCTP_3; 1.
PE 3: Inferred from homology;
KW Calcium; Cytoplasm.
FT CHAIN 1..171
FT /note="Translationally-controlled tumor protein homolog"
FT /id="PRO_0000211289"
FT DOMAIN 1..171
FT /note="TCTP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ SEQUENCE 171 AA; 19874 MW; 58EF2D2005214002 CRC64;
MKVYKDIFTN DEVCSDSYIQ EDPFGNAEFR EIAFEVKSNK RIKGNDDYGI ADNSEDAVDG
MGADVEHVID IVDSFQLTST SLSKKEYSAY VKNFMQRILK HLEEKKPDRV NIFKTKAQPL
IKHILTNFDD FEFYMGESLD MEAGLIYSYY KGEEITPRFV YISDGLFEEK Y