ID   TCTP_PLAKN              Reviewed;         171 AA.
AC   P84152;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=TCTP;
OS   Plasmodium knowlesi.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5850;
RN   [1] {ECO:0000312|PDB:1TXJ}
RP   X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS).
RA   Walker J.R., Vedadi M., Sharma S., Houston S., Lew J., Amani M., Wasney G.,
RA   Skarina T., Bray J., Hui R.;
RT   "Crystal structure and biophysical characterization of translationally
RT   controlled tumour-associated protein (TCTP) from Plasmodium knowlesi.";
RL   Submitted (JUL-2004) to the PDB data bank.
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   PDB; 1TXJ; X-ray; 2.00 A; A=1-171.
DR   PDBsum; 1TXJ; -.
DR   AlphaFoldDB; P84152; -.
DR   SMR; P84152; -.
DR   VEuPathDB; PlasmoDB:PKA1H_100027700; -.
DR   VEuPathDB; PlasmoDB:PKNH_1022600; -.
DR   VEuPathDB; PlasmoDB:PKNOH_S07460700; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   EvolutionaryTrace; P84152; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Calcium; Cytoplasm.
FT   CHAIN           1..171
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211292"
FT   DOMAIN          1..171
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
FT   STRAND          2..6
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   TURN            7..9
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          12..15
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           23..25
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           27..29
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   TURN            30..32
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          33..37
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          40..43
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          67..69
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           70..75
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          78..80
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           84..105
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           107..109
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           110..126
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           128..130
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          132..135
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          146..149
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          158..162
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   HELIX           163..165
FT                   /evidence="ECO:0007829|PDB:1TXJ"
FT   STRAND          166..170
FT                   /evidence="ECO:0007829|PDB:1TXJ"
SQ   SEQUENCE   171 AA;  19854 MW;  319D5FA986F5825D CRC64;
     MKVYKDVFTN DEVCSDSYNQ EDPFGIADFR EIAFEVKSNK RIKGNDDYGI ADNSEEAVDG
     MGADVEQVID IVDSFQLTST SLSKKEYSVY IKNYMQKILK YLEEKKPDRV DVFKTKAQPL
     IKHILTNFDD FEFYMGESLD MDAGLTYSYY KGEEVTPRFV YISDGLYEEK F