TCX7_ARATH
ID TCX7_ARATH Reviewed; 459 AA.
AC F4JY84;
DT 11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Protein tesmin/TSO1-like CXC 7;
DE Short=AtTCX7;
GN Name=TCX7; OrderedLocusNames=At5g25790; ORFNames=F18A17.40;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY, NOMENCLATURE, AND ZINC-BINDING.
RX PubMed=18057042; DOI=10.1093/jxb/erm215;
RA Andersen S.U., Algreen-Petersen R.G., Hoedl M., Jurkiewicz A.,
RA Cvitanich C., Braunschweig U., Schauser L., Oh S.A., Twell D., Jensen E.O.;
RT "The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds
RT zinc in vitro and TSO1 is required for both male and female fertility in
RT Arabidopsis thaliana.";
RL J. Exp. Bot. 58:3657-3670(2007).
CC -!- FUNCTION: Plays a role in development of both male and female
CC reproductive tissues. {ECO:0000250}.
CC -!- INTERACTION:
CC F4JY84; O23210: SCL15; NbExp=3; IntAct=EBI-15193079, EBI-15193077;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DOMAIN: The cysteine-rich domain CRC binds zinc in vitro.
CC -!- SIMILARITY: Belongs to the lin-54 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BX830951; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC005405; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93488.1; -; Genomic_DNA.
DR EMBL; BX830951; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_197951.2; NM_122480.3.
DR AlphaFoldDB; F4JY84; -.
DR SMR; F4JY84; -.
DR BioGRID; 17923; 2.
DR IntAct; F4JY84; 2.
DR STRING; 3702.AT5G25790.1; -.
DR PaxDb; F4JY84; -.
DR PRIDE; F4JY84; -.
DR EnsemblPlants; AT5G25790.1; AT5G25790.1; AT5G25790.
DR GeneID; 832648; -.
DR Gramene; AT5G25790.1; AT5G25790.1; AT5G25790.
DR KEGG; ath:AT5G25790; -.
DR Araport; AT5G25790; -.
DR TAIR; locus:2145294; AT5G25790.
DR eggNOG; KOG1171; Eukaryota.
DR HOGENOM; CLU_020949_0_0_1; -.
DR InParanoid; F4JY84; -.
DR OMA; LMCDEQG; -.
DR PhylomeDB; F4JY84; -.
DR PRO; PR:F4JY84; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4JY84; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR005172; CRC.
DR InterPro; IPR028307; Lin-54_fam.
DR InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR PANTHER; PTHR12446; PTHR12446; 1.
DR Pfam; PF03638; TCR; 2.
DR SMART; SM01114; CXC; 2.
DR PROSITE; PS51634; CRC; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Metal-binding; Nucleus; Reference proteome; Zinc.
FT CHAIN 1..459
FT /note="Protein tesmin/TSO1-like CXC 7"
FT /id="PRO_0000418172"
FT DOMAIN 93..217
FT /note="CRC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00971"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 51357 MW; 071E4AFDEA4FBB1A CRC64;
MEDLSNQNLL PRQSDISIPA EKMDSFQKSL EPPPCSPVKS SQQSETEVTP PQKPPLHQFG
HNQVQKNRVS NQDPSTSRRH NEVESKENTP NKQQKHCNCK NSKCLKLYCE CFASGSYCNG
CNCVNCHNKL ENESSRQVAI SGILERNPDA FKPKIAGSPH GMKDLQENVQ QVLLIGKHSK
GCHCRKSGCL KKYCECYQAN ILCSENCRCQ DCKNFEGSEE RKALLHGSQV SDTYIQQMTN
AAVNRAIDMS AYLYPPESRK RKSKDISDSV VSSYGVQYQR ANHVRRNGEN SLFSLPNNKA
VSGSTTSAYR SSWSNTFQPH HVRELCSLLV SNSVDVANKL SDKGRKNDKG PSSLDGAQRV
ANEINDSPDC VLDANRMDEK PISPATRALM CDEEHEIGSE KETSARVKTS QEKEDTDTSS
GIYLEQERQI LSIFRDYLIQ LSNRARINGK NIKSNTNPS
