ID   TDA11_ASHGO             Reviewed;         364 AA.
AC   Q75AS0;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; OrderedLocusNames=ADL150C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51770.2; -; Genomic_DNA.
DR   RefSeq; NP_983946.2; NM_209299.2.
DR   AlphaFoldDB; Q75AS0; -.
DR   SMR; Q75AS0; -.
DR   STRING; 33169.AAS51770; -.
DR   EnsemblFungi; AAS51770; AAS51770; AGOS_ADL150C.
DR   GeneID; 4620088; -.
DR   KEGG; ago:AGOS_ADL150C; -.
DR   eggNOG; ENOG502S2SD; Eukaryota.
DR   HOGENOM; CLU_762843_0_0_1; -.
DR   InParanoid; Q75AS0; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031388; Tda11.
DR   Pfam; PF17084; TDA11; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..364
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410754"
FT   REGION          1..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          94..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          263..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          324..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          139..181
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        18..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   364 AA;  39297 MW;  813421FB14138CCF CRC64;
     MEHNASDAVG TRDAGWQTDM CHRTSGTAEQ GGSKNKGRGG RREQSHIRAY SSASADGYRM
     HRNHTGGAES PGAEQGTPPR RNSVLKRRSL IQTIMSPEGG AASPERGRRS VSLYSPASAG
     SDEGDVGAML QTLATRELAL LEQRKTVEDL RRALRLEERV LVAQARELEE LKQRVARALD
     AGSPRAVLEP GAELPGAPGA RESVWAKSMS FLNEFDQILQ EGLEKRLGFD ELMPSPATDA
     TTPEADDRRG IWGLVSEFKA GLLGLSDSTP PPDAPAAYLE KQRNRSVGPE PRRTNTGDAV
     AEHSRDARYA RKRDLHEQAY SPADAAAENG VVTGGRLGAT PHSSGSIRKR CPPLSTSVEM
     QNYV