ID   TDA11_CANGA             Reviewed;         489 AA.
AC   Q6FR01;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; OrderedLocusNames=CAGL0I02112g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
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DR   EMBL; CR380955; CAG60280.1; -; Genomic_DNA.
DR   RefSeq; XP_447343.1; XM_447343.1.
DR   AlphaFoldDB; Q6FR01; -.
DR   SMR; Q6FR01; -.
DR   STRING; 284593.Q6FR01; -.
DR   EnsemblFungi; CAG60280; CAG60280; CAGL0I02112g.
DR   GeneID; 2888981; -.
DR   KEGG; cgr:CAGL0I02112g; -.
DR   CGD; CAL0132072; CAGL0I02112g.
DR   VEuPathDB; FungiDB:CAGL0I02112g; -.
DR   eggNOG; ENOG502S2SD; Eukaryota.
DR   HOGENOM; CLU_046807_0_0_1; -.
DR   InParanoid; Q6FR01; -.
DR   OMA; WSFVSDV; -.
DR   Proteomes; UP000002428; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031388; Tda11.
DR   Pfam; PF17084; TDA11; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..489
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410755"
FT   REGION          1..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          263..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          344..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          391..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          439..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          210..266
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        14..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..107
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..199
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        263..281
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..321
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  54919 MW;  7ED708540A2CDAB0 CRC64;
     MDQKFDEFIA QTESEAEIDT SSRYTTGSIS PQFASPTKFK NVLPHETDTQ TGQRNRVAEH
     QHVPKSLLNA SVEESHNHPL KEDKSESRQR QVSVSNSNPS SKGMVNKRRS LIQPMMVPTT
     PETDRTRPQS QSNVASGNSA NKNNLHPDTN HGIDINATTQ TPSSMSMGNP KFSENFASLA
     PSSKRNSMHS RTSSSQSMAI DSSLGGSMDV NALLQSLANK ELELLECKRK IDDLKKQLHM
     EENIYQNKAN ELQELKNKVS KNINVSGSNQ PVFNKTSTTG RKNSRESSRR NTHVTPVKTT
     RNDIRQDTSL NQDMENTDDN KQSMWSKPLA LFNQVDQIIQ QELERTLNWD EPPTPVEETE
     ENQEGDKSVS KSLWSFVSDL KTGLLGIEEE EDGHHTQQSN SNVNRPKNTH GQVMDNRKHA
     NEDINLSIKE FKTTKKHLDD NSDTHLKQRS GRTAVRKTKS GNKLNFVDDS DDGDSTLEAD
     MVEMGSFSR