ID   TDA11_DEBHA             Reviewed;         463 AA.
AC   Q6BXG5;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 2.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; OrderedLocusNames=DEHA2B03212g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
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DR   EMBL; CR382134; CAG85095.2; -; Genomic_DNA.
DR   RefSeq; XP_457104.2; XM_457104.1.
DR   AlphaFoldDB; Q6BXG5; -.
DR   SMR; Q6BXG5; -.
DR   EnsemblFungi; CAG85095; CAG85095; DEHA2B03212g.
DR   GeneID; 2913122; -.
DR   KEGG; dha:DEHA2B03212g; -.
DR   VEuPathDB; FungiDB:DEHA2B03212g; -.
DR   eggNOG; ENOG502SETW; Eukaryota.
DR   HOGENOM; CLU_046869_1_0_1; -.
DR   InParanoid; Q6BXG5; -.
DR   OMA; EMCIVEL; -.
DR   OrthoDB; 1527178at2759; -.
DR   Proteomes; UP000000599; Chromosome B.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..463
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410756"
FT   REGION          1..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          281..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          145..177
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..107
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..304
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..346
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        400..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   463 AA;  50728 MW;  FB8E7DA42BDB4CB4 CRC64;
     MNGSTSSDAV DPGLCVTTPS PVKQTLTLGS DTFNKDDKQI TPSIRRSNST RSKGINFNVA
     ISPLATGQTP PSSKGGHRKT ASYDAKNLHL PQLAESSPSS TIPDSPIPTA SEELKYDLPL
     PSTEQLMGLD IDDQLRLLAL KEMSIVEIKD SIGNLTSKLQ RNENELHSLR EVIQRSLYKE
     LNSSSSKSKK ETSSNGFVTR PQRQNSNPRE EAIASTKNRS RRRTLSSSSS GVPPVLSSQQ
     LSQNTDKQSR RDSTLWSNLS KPLNLIQQFD SMLQHEFEKS MIPQKNQEGS DKTMDSHKSR
     HSEDSTSSLG SISSPLNSKS KSVTGKQSND ELDRYFAQQS TSGASKDKPD GVVPTESHMN
     SDDMIQAVSS SIWSFVNDVK TNVLSSLADE DVPESRSHVT KGPSGFSNSN DQKEINDLTV
     YNLDTGSTVS LDKNEDSDLD YTFVHNTANE DRAAVDHDKS KND