ID   TDA11_PICGU             Reviewed;         391 AA.
AC   A5DH34;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; ORFNames=PGUG_02585;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
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DR   EMBL; CH408157; EDK38487.2; -; Genomic_DNA.
DR   RefSeq; XP_001484856.1; XM_001484806.1.
DR   AlphaFoldDB; A5DH34; -.
DR   SMR; A5DH34; -.
DR   EnsemblFungi; EDK38487; EDK38487; PGUG_02585.
DR   GeneID; 5126667; -.
DR   KEGG; pgu:PGUG_02585; -.
DR   VEuPathDB; FungiDB:PGUG_02585; -.
DR   eggNOG; ENOG502SETW; Eukaryota.
DR   HOGENOM; CLU_046869_1_0_1; -.
DR   InParanoid; A5DH34; -.
DR   OMA; EMCIVEL; -.
DR   OrthoDB; 1527178at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..391
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410759"
FT   REGION          1..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          265..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..223
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        338..352
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..391
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   391 AA;  43856 MW;  7AD24E15E4C67990 CRC64;
     MDLTPSPRKH RSVSHSQSSD SGPPSSTKSN SGVPAGSNRK GFNINIAVSP ISVSSPPVSH
     KHTLTRSHSH SSKHRRGSSA STNNPLPQLL EDADGPQLPE WPQPANESQG LRYNLELPSD
     EHLASLDIDD QLKFLALKEM GIVELKDKIS QLNSILHKGE KDLHRLRELV QRSLYKEMSA
     GYTGSSKHVR QSSNPRDEAI ASTKNRTRRR TLSSSSSPSK YLPVPEQSEP DSKSRLWSNL
     SKPLGFIQQF DSMLQNEFER SLIPQVSNSA NPQPRTSEES YQSPLRSRSK NNDVDLPTEW
     TSSRSSSPQR ASRNPEEMFQ AVSSSIWSFV NDVRENMLPP REEEEKDKEL YNLDNGSTVS
     VENMNNSDYD ETTTETLPRR RSRQNSNAID K