ID   TDA11_VANPO             Reviewed;         513 AA.
AC   A7TEW6;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; ORFNames=Kpol_1050p70;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
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DR   EMBL; DS480381; EDO19212.1; -; Genomic_DNA.
DR   RefSeq; XP_001647070.1; XM_001647020.1.
DR   AlphaFoldDB; A7TEW6; -.
DR   SMR; A7TEW6; -.
DR   STRING; 436907.A7TEW6; -.
DR   EnsemblFungi; EDO19212; EDO19212; Kpol_1050p70.
DR   GeneID; 5547545; -.
DR   KEGG; vpo:Kpol_1050p70; -.
DR   eggNOG; ENOG502S2SD; Eukaryota.
DR   HOGENOM; CLU_046807_0_0_1; -.
DR   InParanoid; A7TEW6; -.
DR   OMA; WSFVSDV; -.
DR   OrthoDB; 1540211at2759; -.
DR   PhylomeDB; A7TEW6; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031388; Tda11.
DR   Pfam; PF17084; TDA11; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..513
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410760"
FT   REGION          26..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          347..400
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          417..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          190..240
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        32..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..180
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..450
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   513 AA;  56586 MW;  35CF4287C92669E7 CRC64;
     MDSDNVDESV GMLDLKTKFD VFIENGDKNL EMDTGTRATT VPNTPTSDTK NSNSHSSVSP
     LRSFSRRSGT GSSVGSTAGK TNLSPQLLTP VRLNEGEHPL KDIPSANGSN VKSKSNNKSK
     RRSLIQPITA PISPDHHGNN FSSAGPVASE TRKLSGHQRV ISNTSMHSRR SSSQSIMNDV
     SQDGSLGISS LLQSLASKEL ELLETKQRIE DLRRQLASEE NAYNQGALEL KSLKEQVSSY
     LNPTTFGSNN NNHSIQIADG QDYVIDSTTN ELIPTISRAE SETKLNIPKS SNSISSGNSK
     IHSRALSNLS PKQEEGQEDE ANESIWSKSL SMFTRLDQII QQEVEKSLNW ESSPEPTAST
     FAPITEEPGQ YYDQNSNSFV RESSRQQNSH NSSEANDNSY SSRSIWNFVS EVKTGLLGKP
     DDELKGSKPQ INTKTDSLEF SNASDDANDS PTIEYNIKQF KTRRKVTGDV EVENSSSKLR
     DVSIGDNVEE DDNENRIRQV NNRRKVVEMI DFN