ID   TDA11_YEAS2             Reviewed;         504 AA.
AC   C7GJX9;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; ORFNames=C1Q_00499;
OS   Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=574961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAY291;
RX   PubMed=19812109; DOI=10.1101/gr.091777.109;
RA   Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA   Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA   Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA   Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA   Pereira G.A.G.;
RT   "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT   bioethanol production.";
RL   Genome Res. 19:2258-2270(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACFL01000017; EEU08889.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7GJX9; -.
DR   SMR; C7GJX9; -.
DR   Proteomes; UP000008073; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031388; Tda11.
DR   Pfam; PF17084; TDA11; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Phosphoprotein.
FT   CHAIN           1..504
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410762"
FT   REGION          32..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          252..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          400..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          179..231
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        252..288
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..303
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        400..432
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        433..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..480
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..504
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         236
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P38854"
FT   MOD_RES         244
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P38854"
FT   MOD_RES         286
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P38854"
SQ   SEQUENCE   504 AA;  56314 MW;  AE8B894335D1DB63 CRC64;
     MNKFDEFIES NEKDLDVDTS TRNSIISMSP VRKTGRKIRS ASSNGYRLEH HRTSSAGSMH
     SQRLMTPTRL NDQDHPLQAK PDARRVVTRH SSVSVPNAMS KRRSLIQPMV VPTTPESQNN
     LPSVSHSEGS YGIPLESTTV LSSEQAMASG LRRSRNGSSQ SVNSMIATTI PTNGVDVSAL
     LQSLATKELE LLECKQKIED LKKQTQHEEQ NYTRRARELH ELKEQVSKHL DPSLNTPVKN
     RAFSPVYQNI PLESRTENAG NSSLPSSVSK PKNMGHQSTN QSRSVSPQDI QERRQRDDSS
     DSSKQSLWSK PLALFNQFDK IIQHEIERTL NWDDSLSGTP EVQEGTPTSN SESSAQQYDN
     EAPGARQKSP SQGSVSRSLW SFVSDVKAGL LGIEEENDND VITDNRCDPV YKSDRQHEQK
     KSTHKITNRG QAEDSGDDSS LNMRKFKTTT KFQKDNAGNN SLTDESGHRT REKKSKRSSN
     KLSFIGEPDN DNSSVKNSVE MTDF