ID   TDA11_ZYGRC             Reviewed;         422 AA.
AC   C5DRG2;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Topoisomerase I damage affected protein 11;
GN   Name=TDA11; OrderedLocusNames=ZYRO0B08206g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TDA11 family. {ECO:0000305}.
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DR   EMBL; CU928174; CAR26373.1; -; Genomic_DNA.
DR   RefSeq; XP_002495306.1; XM_002495261.1.
DR   AlphaFoldDB; C5DRG2; -.
DR   SMR; C5DRG2; -.
DR   STRING; 559307.C5DRG2; -.
DR   EnsemblFungi; CAR26373; CAR26373; ZYRO0B08206g.
DR   GeneID; 8202458; -.
DR   KEGG; zro:ZYRO0B08206g; -.
DR   HOGENOM; CLU_046807_0_0_1; -.
DR   InParanoid; C5DRG2; -.
DR   Proteomes; UP000008536; Chromosome B.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031388; Tda11.
DR   Pfam; PF17084; TDA11; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..422
FT                   /note="Topoisomerase I damage affected protein 11"
FT                   /id="PRO_0000410770"
FT   REGION          15..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          203..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          309..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          382..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          155..208
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        20..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        203..226
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..244
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..422
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   422 AA;  47712 MW;  03BBA319CDB8FE4D CRC64;
     MNKFDEFVEA TDKELHVDTS TRNTTINVSS PGSSNDSTSS PKSPSGEVLS RKEMKMKQFT
     PKKLNYQDHP LKDHSTGGSL PITRRTSRSS TIHKRKSLLQ PIVAPQTPDK SGPSWRSNGG
     SPSGSFNRQR STSGASMHSR SSSQSLSLDS TFDVSLQNLA NKELELLESK RRIEELKKQL
     QLEEQSYQKR VEELKELKSQ VSNDLQINSQ HQQQQQQQQQ QQQQHHLQPH SKKREEHTRD
     KSRGKGSGTG SSSVWSKPLA FFNQFDQIIQ HELERSLRWD DTPEDKIMQP EPYEGAAAVQ
     NSQLRQPQVE IPTSNSQSNV NNTDNNDNKI NNNTNNTSNN KNGHDDNNNN NDSSNNNNNN
     DGNNKNLWSF FNDVKTGLLG IEEEEETPQR TIAGSAKNDN GIKEFKTAKK TRDPVEMTDF
     QK