ID   TDA2_YEAS1              Reviewed;         126 AA.
AC   B3LRI8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Topoisomerase I damage affected protein 2;
GN   Name=TDA2; ORFNames=SCRG_04546;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P40045}. Cell
CC       projection {ECO:0000250|UniProtKB:P40045}. Note=Concentrates at
CC       cytoplasmic punctate structures and localizes at the mating projection
CC       tip. {ECO:0000250|UniProtKB:P40045}.
CC   -!- SIMILARITY: Belongs to the TDA2 family. {ECO:0000305}.
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DR   EMBL; CH408052; EDV08901.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LRI8; -.
DR   SMR; B3LRI8; -.
DR   EnsemblFungi; EDV08901; EDV08901; SCRG_04546.
DR   HOGENOM; CLU_137494_1_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.1140.40; -; 1.
DR   InterPro; IPR005334; Tctex-1-like.
DR   InterPro; IPR038586; Tctex-1-like_sf.
DR   Pfam; PF03645; Tctex-1; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cell projection; Cytoplasm.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P40045"
FT   CHAIN           2..126
FT                   /note="Topoisomerase I damage affected protein 2"
FT                   /id="PRO_0000410734"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:P40045"
SQ   SEQUENCE   126 AA;  14471 MW;  2F5CD27AF0D386E3 CRC64;
     MSMQIEIKDG RSDNSPLPER KLVTLIQESY DSLKDDNEIN LSTESTSNLL IKLVLEKLEK
     HSSLYKYIAS VTTLNIEGLN EENANFSLKN DIGASWESKK DGIFNYKLED KNSNECYLIT
     ILWLHK