ID   TDA2_YEAS2              Reviewed;         126 AA.
AC   C7GRQ3;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Topoisomerase I damage affected protein 2;
GN   Name=TDA2; ORFNames=C1Q_03053;
OS   Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=574961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAY291;
RX   PubMed=19812109; DOI=10.1101/gr.091777.109;
RA   Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA   Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA   Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA   Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA   Pereira G.A.G.;
RT   "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT   bioethanol production.";
RL   Genome Res. 19:2258-2270(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P40045}. Cell
CC       projection {ECO:0000250|UniProtKB:P40045}. Note=Concentrates at
CC       cytoplasmic punctate structures and localizes at the mating projection
CC       tip. {ECO:0000250|UniProtKB:P40045}.
CC   -!- SIMILARITY: Belongs to the TDA2 family. {ECO:0000305}.
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DR   EMBL; ACFL01000153; EEU06510.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7GRQ3; -.
DR   SMR; C7GRQ3; -.
DR   Proteomes; UP000008073; Unassembled WGS sequence.
DR   GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.1140.40; -; 1.
DR   InterPro; IPR005334; Tctex-1-like.
DR   InterPro; IPR038586; Tctex-1-like_sf.
DR   Pfam; PF03645; Tctex-1; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cell projection; Cytoplasm.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P40045"
FT   CHAIN           2..126
FT                   /note="Topoisomerase I damage affected protein 2"
FT                   /id="PRO_0000410735"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:P40045"
SQ   SEQUENCE   126 AA;  14498 MW;  2F5CD27AF0C9AFE3 CRC64;
     MSMQIEIKDG RSDNSPLPER KLVTLIQESY DSLKDDNEIN LSTESTSNLL IKLVLEKLEK
     HSSLYKYIAS VTTLNIEGLN EENANFSLKN DIGASWESKK DGIFNYKLED KNNNECYLIT
     ILWLHK