ID   TDA2_YEASL              Reviewed;         124 AA.
AC   E7KMP1;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Topoisomerase I damage affected protein 2;
GN   Name=TDA2; ORFNames=QA23_1345;
OS   Saccharomyces cerevisiae (strain Lalvin QA23) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=764098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin QA23;
RX   PubMed=21304888; DOI=10.1371/journal.pgen.1001287;
RA   Borneman A.R., Desany B.A., Riches D., Affourtit J.P., Forgan A.H.,
RA   Pretorius I.S., Egholm M., Chambers P.J.;
RT   "Whole-genome comparison reveals novel genetic elements that characterize
RT   the genome of industrial strains of Saccharomyces cerevisiae.";
RL   PLoS Genet. 7:E1001287-E1001287(2011).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P40045}. Cell
CC       projection {ECO:0000250|UniProtKB:P40045}. Note=Concentrates at
CC       cytoplasmic punctate structures and localizes at the mating projection
CC       tip. {ECO:0000250|UniProtKB:P40045}.
CC   -!- SIMILARITY: Belongs to the TDA2 family. {ECO:0000305}.
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DR   EMBL; ADVV01000029; EGA83126.1; -; Genomic_DNA.
DR   AlphaFoldDB; E7KMP1; -.
DR   SMR; E7KMP1; -.
DR   EnsemblFungi; EGA83126; EGA83126; QA23_1345.
DR   HOGENOM; CLU_137494_1_0_1; -.
DR   GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.1140.40; -; 1.
DR   InterPro; IPR005334; Tctex-1-like.
DR   InterPro; IPR038586; Tctex-1-like_sf.
DR   Pfam; PF03645; Tctex-1; 1.
PE   3: Inferred from homology;
KW   Cell projection; Cytoplasm.
FT   CHAIN           1..124
FT                   /note="Topoisomerase I damage affected protein 2"
FT                   /id="PRO_0000410740"
SQ   SEQUENCE   124 AA;  14253 MW;  2F5CA7CC262825AE CRC64;
     MQIEIKDGRS DNSPLPERKL VTLIQESYDS LKDDNEINLS TESTSNLLIK LVLEKLEKHS
     SLYKYIASVT TLNIEGLNEE NANFSLKNDI GASWESKKDG IFNYKLEDKN SNECYLITIL
     WLHK