ID   TDCR_ECOLI              Reviewed;          72 AA.
AC   P11866; P76667; Q2M988;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=Threonine dehydratase operon activator protein;
GN   Name=tdcR; OrderedLocusNames=b3119, JW5525;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=2660107; DOI=10.1093/nar/17.10.3994;
RA   Schweizer H., Datta P.;
RT   "The complete nucleotide sequence of the tdc region of Escherichia coli.";
RL   Nucleic Acids Res. 17:3994-3994(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=2573820; DOI=10.1007/bf00332418;
RA   Schweizer H.P., Datta P.;
RT   "Identification and DNA sequence of tdcR, a positive regulatory gene of the
RT   tdc operon of Escherichia coli.";
RL   Mol. Gen. Genet. 218:516-522(1989).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   IDENTIFICATION OF START CODON.
RX   PubMed=7928991; DOI=10.1128/jb.176.20.6214-6220.1994;
RA   Hagewood B.T., Ganduri Y.L., Datta P.;
RT   "Functional analysis of the tdcABC promoter of Escherichia coli: roles of
RT   TdcA and TdcR.";
RL   J. Bacteriol. 176:6214-6220(1994).
CC   -!- FUNCTION: Probable trans-acting positive activator for the tdc operon.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA57923.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAA32591.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAA34464.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X14430; CAA32591.1; ALT_INIT; Genomic_DNA.
DR   EMBL; X16445; CAA34464.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U18997; AAA57923.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76154.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77168.1; -; Genomic_DNA.
DR   PIR; D65101; BVECTD.
DR   RefSeq; NP_417589.4; NC_000913.3.
DR   RefSeq; WP_001301311.1; NZ_LN832404.1.
DR   AlphaFoldDB; P11866; -.
DR   BioGRID; 4262421; 6.
DR   STRING; 511145.b3119; -.
DR   PaxDb; P11866; -.
DR   PRIDE; P11866; -.
DR   EnsemblBacteria; AAC76154; AAC76154; b3119.
DR   EnsemblBacteria; BAE77168; BAE77168; BAE77168.
DR   GeneID; 944907; -.
DR   KEGG; ecj:JW5525; -.
DR   KEGG; eco:b3119; -.
DR   PATRIC; fig|511145.12.peg.3213; -.
DR   EchoBASE; EB0985; -.
DR   HOGENOM; CLU_2715938_0_0_6; -.
DR   OMA; HDRTSFC; -.
DR   BioCyc; EcoCyc:PD03292; -.
DR   PRO; PR:P11866; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:EcoCyc.
PE   4: Predicted;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..72
FT                   /note="Threonine dehydratase operon activator protein"
FT                   /id="PRO_0000072472"
SQ   SEQUENCE   72 AA;  8608 MW;  1F8F01130704C897 CRC64;
     MSKFSNFIIN KPFSVINNAA CHIFSRYLLE NKHLFYQYFK ISNTCIDHLE QLINVNFFSS
     DRTSFCECNR FP