TDL1A_ORYSJ
ID TDL1A_ORYSJ Reviewed; 226 AA.
AC Q2QR54; A0A0P0Y9Z3;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=TPD1 protein homolog 1A {ECO:0000305};
DE AltName: Full=Protein MICROSPORELESS 2 {ECO:0000303|PubMed:22913653};
DE AltName: Full=TPD1-like protein 1A {ECO:0000303|PubMed:18248596};
DE Short=OsTDL1A {ECO:0000303|PubMed:18248596};
DE Flags: Precursor;
GN Name=TDL1A {ECO:0000303|PubMed:18248596};
GN Synonyms=MIL2 {ECO:0000303|PubMed:22913653};
GN OrderedLocusNames=Os12g0472500 {ECO:0000312|EMBL:BAF29772.1},
GN LOC_Os12g28750 {ECO:0000312|EMBL:ABA98465.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP FUNCTION, INTERACTION WITH MSP1, AND TISSUE SPECIFICITY.
RX PubMed=18248596; DOI=10.1111/j.1365-313x.2008.03426.x;
RA Zhao X., de Palma J., Oane R., Gamuyao R., Luo M., Chaudhury A., Herve P.,
RA Xue Q., Bennett J.;
RT "OsTDL1A binds to the LRR domain of rice receptor kinase MSP1, and is
RT required to limit sporocyte numbers.";
RL Plant J. 54:375-387(2008).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, AND MUTAGENESIS OF GLN-83.
RX PubMed=22913653; DOI=10.1111/j.1469-8137.2012.04270.x;
RA Hong L., Tang D., Shen Y., Hu Q., Wang K., Li M., Lu T., Cheng Z.;
RT "MIL2 (MICROSPORELESS2) regulates early cell differentiation in the rice
RT anther.";
RL New Phytol. 196:402-413(2012).
CC -!- FUNCTION: Involved in cell specification during anther development.
CC Required for the differentiation of primary parietal cells into
CC secondary parietal cells in anthers (PubMed:22913653). May serve as an
CC extracellular ligand for the MSP1 receptor kinase to limit sporocyte
CC number in ovules (PubMed:18248596). {ECO:0000269|PubMed:18248596,
CC ECO:0000269|PubMed:22913653}.
CC -!- SUBUNIT: Interacts with MSP1. {ECO:0000269|PubMed:18248596}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, and anthers and ovules during
CC meiosis. {ECO:0000269|PubMed:18248596}.
CC -!- DISRUPTION PHENOTYPE: Male-sterile phenotype due to the absence of
CC tapetal cells in the developing anthers. {ECO:0000269|PubMed:22913653}.
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DR EMBL; AL713941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DP000011; ABA98465.1; -; Genomic_DNA.
DR EMBL; AP008218; BAF29772.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT17103.1; -; Genomic_DNA.
DR EMBL; AK108523; BAG98429.1; -; mRNA.
DR RefSeq; XP_015619000.1; XM_015763514.1.
DR AlphaFoldDB; Q2QR54; -.
DR STRING; 4530.OS12T0472500-01; -.
DR PaxDb; Q2QR54; -.
DR PRIDE; Q2QR54; -.
DR EnsemblPlants; Os12t0472500-01; Os12t0472500-01; Os12g0472500.
DR GeneID; 4352199; -.
DR Gramene; Os12t0472500-01; Os12t0472500-01; Os12g0472500.
DR KEGG; osa:4352199; -.
DR eggNOG; ENOG502S0K4; Eukaryota.
DR HOGENOM; CLU_050138_0_0_1; -.
DR InParanoid; Q2QR54; -.
DR OMA; YQGRATA; -.
DR OrthoDB; 1541320at2759; -.
DR PlantReactome; R-OSA-8986768; Anther and pollen development.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR Genevisible; Q2QR54; OS.
DR GO; GO:0010234; P:anther wall tapetum cell fate specification; IMP:UniProtKB.
DR GO; GO:0001709; P:cell fate determination; IBA:GO_Central.
DR GO; GO:0009556; P:microsporogenesis; IMP:UniProtKB.
DR InterPro; IPR040361; TPD1.
DR PANTHER; PTHR33184; PTHR33184; 1.
PE 1: Evidence at protein level;
KW Differentiation; Reference proteome; Signal.
FT SIGNAL 1..35
FT /evidence="ECO:0000255"
FT CHAIN 36..226
FT /note="TPD1 protein homolog 1A"
FT /evidence="ECO:0000255"
FT /id="PRO_0000432095"
FT MUTAGEN 83
FT /note="Q->P: In mil2-2; defective in early anther
FT development."
FT /evidence="ECO:0000269|PubMed:22913653"
SQ SEQUENCE 226 AA; 22734 MW; D01755021B35E5AD CRC64;
MRVSSASSTP PPPAFAAAAW AVVLLAMLRS DVALAAAASS NDDTGLSPLM PPPPLAAPVP
AAVSPAPATP PAVLSPRKLL RPQGADVVGV GFVSGSGGGG GGDGVRTRRV DDGCAGADDI
AIYQGRATPL PSGVPAYTVD VMNRCAGGGG GDEECAIAGI HVRCGWFSSV SLVDPRVFRR
LGHDDCLLND GRPLLAGETV SFEYTNSFPY KLSVSVATCV VDPAAP
