TDP1L_MOUSE
ID TDP1L_MOUSE Reviewed; 365 AA.
AC P0DMR6; Q717B3; Q71G58; Q8BZV7; Q8VI39;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 07-JAN-2015, sequence version 1.
DT 03-AUG-2022, entry version 40.
DE RecName: Full=TD and POZ domain-containing protein 1-like {ECO:0000305};
GN Name=Gm9125 {ECO:0000312|MGI:MGI:3702970};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Colon;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SIMILARITY: Belongs to the Tdpoz family. {ECO:0000305}.
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DR EMBL; AK033449; BAC28295.1; -; mRNA.
DR CCDS; CCDS57232.1; -.
DR RefSeq; NP_001157202.1; NM_001163730.2.
DR AlphaFoldDB; P0DMR6; -.
DR SMR; P0DMR6; -.
DR STRING; 10090.ENSMUSP00000136341; -.
DR PaxDb; P0DMR6; -.
DR PRIDE; P0DMR6; -.
DR Ensembl; ENSMUST00000177735; ENSMUSP00000136341; ENSMUSG00000095822.
DR Ensembl; ENSMUST00000178458; ENSMUSP00000136564; ENSMUSG00000094328.
DR Ensembl; ENSMUST00000180746; ENSMUSP00000138015; ENSMUSG00000094328.
DR Ensembl; ENSMUST00000193529; ENSMUSP00000141802; ENSMUSG00000095822.
DR GeneID; 668359; -.
DR KEGG; mmu:668359; -.
DR UCSC; uc008qfq.1; mouse.
DR CTD; 668359; -.
DR MGI; MGI:3702970; Gm9125.
DR VEuPathDB; HostDB:ENSMUSG00000094328; -.
DR VEuPathDB; HostDB:ENSMUSG00000095822; -.
DR eggNOG; KOG1987; Eukaryota.
DR GeneTree; ENSGT00940000154376; -.
DR HOGENOM; CLU_004253_2_0_1; -.
DR OMA; DFLVIKC; -.
DR OrthoDB; 864323at2759; -.
DR PhylomeDB; P0DMR6; -.
DR BioGRID-ORCS; 668359; 1 hit in 29 CRISPR screens.
DR PRO; PR:P0DMR6; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; P0DMR6; protein.
DR Bgee; ENSMUSG00000094328; Expressed in ileum and 4 other tissues.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; ISO:MGI.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; ISO:MGI.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISO:MGI.
DR GO; GO:0000209; P:protein polyubiquitination; ISO:MGI.
DR GO; GO:0030162; P:regulation of proteolysis; IBA:GO_Central.
DR Gene3D; 2.60.210.10; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR008974; TRAF-like.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50144; MATH; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..365
FT /note="TD and POZ domain-containing protein 1-like"
FT /id="PRO_0000431621"
FT DOMAIN 19..149
FT /note="MATH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00129"
FT DOMAIN 188..255
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ SEQUENCE 365 AA; 41674 MW; 94521C44B76C37AB CRC64;
MSEDMEFENW GSTQSSVEKF CYKWTISNFS FCMGGIQRRI TSPVFSSEEN KEVAWCLRVY
PKGADKESKD YLSVYLVLLS HLQSPVWAKF KFWIINSQGE KYQKTKSPIV ECFLTYEQSG
FKKFLPRDLL LSHRNCLLPE DQLTICCKVT ILGRKYNMPS QNITPAIKDP RHLLTDDLGE
LWENSLFTDC CLLVAGHEFR AHKAILAARS PVFRAMFEHE MKESLKTPIK IHNLNPQVFK
EMMSFIYTGK APYLHSHSMA CDVLPAADKY GLVSLKVLCE DAFCRNLSVK NATHTLILAD
LHSTEKLKTQ ALDFIAYYAS EVCETSEWKS MVESHPHLVA EAFQSLASAQ CSFLEPKVIS
GSNQL
