TDX_ORYSJ
ID TDX_ORYSJ Reviewed; 317 AA.
AC Q6ES52;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=TPR repeat-containing thioredoxin TDX;
DE AltName: Full=OsTrx26;
DE AltName: Full=Tetratricoredoxin;
DE Short=OsTDX;
GN OrderedLocusNames=Os09g0401200, LOC_Os09g23650; ORFNames=P0650H04.34;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19825616; DOI=10.1093/mp/ssn076;
RA Chibani K., Wingsle G., Jacquot J.P., Gelhaye E., Rouhier N.;
RT "Comparative genomic study of the thioredoxin family in photosynthetic
RT organisms with emphasis on Populus trichocarpa.";
RL Mol. Plant 2:308-322(2009).
CC -!- FUNCTION: Probable thiol-disulfide oxidoreductase that may participate
CC in various redox reactions and act as chaperone under heat shock. May
CC interact with HSP70 proteins through the TPR repeats (By similarity).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the thioredoxin family. {ECO:0000305}.
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DR EMBL; AP005321; BAD28518.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25034.1; -; Genomic_DNA.
DR EMBL; AP014965; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK063980; BAG88943.1; -; mRNA.
DR RefSeq; XP_015612619.1; XM_015757133.1.
DR RefSeq; XP_015612620.1; XM_015757134.1.
DR AlphaFoldDB; Q6ES52; -.
DR SMR; Q6ES52; -.
DR STRING; 4530.OS09T0401200-01; -.
DR PRIDE; Q6ES52; -.
DR GeneID; 4346999; -.
DR KEGG; osa:4346999; -.
DR eggNOG; KOG0907; Eukaryota.
DR eggNOG; KOG1308; Eukaryota.
DR HOGENOM; CLU_026202_1_0_1; -.
DR InParanoid; Q6ES52; -.
DR OrthoDB; 1482186at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; Q6ES52; OS.
DR GO; GO:0000118; C:histone deacetylase complex; IBA:GO_Central.
DR GO; GO:0030544; F:Hsp70 protein binding; IBA:GO_Central.
DR GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF00085; Thioredoxin; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; SSF48452; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Electron transport; Redox-active center;
KW Reference proteome; Repeat; TPR repeat; Transport.
FT CHAIN 1..317
FT /note="TPR repeat-containing thioredoxin TDX"
FT /id="PRO_0000394847"
FT REPEAT 50..83
FT /note="TPR 1"
FT REPEAT 85..117
FT /note="TPR 2"
FT REPEAT 119..151
FT /note="TPR 3"
FT DOMAIN 189..316
FT /note="Thioredoxin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..26
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 242
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 245
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT SITE 243
FT /note="Contributes to redox potential value"
FT /evidence="ECO:0000250"
FT SITE 244
FT /note="Contributes to redox potential value"
FT /evidence="ECO:0000250"
FT DISULFID 242..245
FT /note="Redox-active"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
SQ SEQUENCE 317 AA; 34981 MW; 0E4827221A9A1E8C CRC64;
MATAGASSFE DEIMESDIEL EGEAVEPDND PPQKMGDPSV EVSDEKRDQA QLCKNKGVDA
FSEGKLDEAI EHLTEAIVLN PTSAIAYATR AVIFVKSKKP NAAIRDADAA LKINPDSAKG
YKSRGMAKAM LGKWEEAAQD LRMAAKLDYD EEIGAELKKV EPNVLKIEEH RKKYERLRKE
RDIKKAEMEK QRKHAEEVSA ASAALKDGDV IAIHSSSELD TKLKAASSLS RLVVLYFTAA
WCGPCRFIGP VCKSLAEKHR NVVFLKVDID ELNSVAYRWN VSSVPSFFFV RNGKEIDKVV
GADKNGLERK VAQHGSS
