ID   TE62_HASHE              Reviewed;          27 AA.
AC   P0CI17;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Augerpeptide hhe6.2;
OS   Hastula hectica (Sea snail) (Impages hectica).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Terebridae; Hastula.
OX   NCBI_TaxID=745793;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=17886885; DOI=10.1002/jez.b.21195;
RA   Imperial J.S., Kantor Y., Watkins M., Heralde F.M. III, Stevenson B.,
RA   Chen P., Hansson K., Stenflo J., Ownby J.P., Bouchet P., Olivera B.M.;
RT   "Venomous auger snail Hastula (Impages) hectica (Linnaeus, 1758): molecular
RT   phylogeny, foregut anatomy and comparative toxinology.";
RL   J. Exp. Zool. B Mol. Dev. Evol. 308:744-756(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin. {ECO:0000250}.
CC   -!- DOMAIN: The cysteine framework is VI/VII (C-C-CC-C-C).
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DR   AlphaFoldDB; P0CI17; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Secreted; Toxin.
FT   PEPTIDE         1..27
FT                   /note="Augerpeptide hhe6.2"
FT                   /id="PRO_0000402141"
FT   DISULFID        4..13
FT                   /evidence="ECO:0000250"
FT   DISULFID        8..20
FT                   /evidence="ECO:0000250"
FT   DISULFID        12..27
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   27 AA;  2940 MW;  9B6D9900FC1E6D1C CRC64;
     ALPCPYGCPL RCCHMTDGVC LRNKQGC